重庆地区妊娠妇女TORCH感染的调查研究  

Investigation of TORCH infections in pregnancy women in Chongqing

作　　者：刘俊 杨柳 何杨 陈庆 

机构地区：[1]重庆市人口和计划生育科学技术研究院技术指导所,重庆400020

出　　处：《中华医院感染学杂志》2015年第22期5250-5252,共3页Chinese Journal of Nosocomiology

基　　金：重庆市科学技术委员会科技攻关基金项目(CSTC2013GGB00001);重庆市人口和计划生育科学技术研究院基金项目(2014CSTC-JBKY-01705)

摘　　要：目的了解妊娠妇女TORCH感染现况,为预防新生儿出生缺陷干预提供参考依据。方法 2013年4-12月采用按比例多阶段分层整群随机抽样方法,抽取11 953例符合生育政策、计划在3个月内怀孕的妊娠妇女进行问卷调查,采集其静脉血,用ELISA法检测TORCH特异性抗体。结果 11 953例妊娠妇女中巨细胞感染率为0.38%、弓形体为0.59%、梅毒为0.89%;其中渝东南地区(6个区县)巨细胞感染率最高为1.19%、一圈地区(22个区县)弓形体感染率最高为0.94%、渝东北地区(11个区县)梅毒感染率最低为0.23%;梅毒感染率随年龄增加而升高,弓形体感染率随文化程度升高而升高,梅毒感染率随着文化程度升高而下降;不同职业妇女弓形体感染率不同,公职人员最高为1.06%、农民最低为0.37%;既往具有不良妊娠结局史的计划妊娠妇女巨细胞、弓形体、梅毒阳性率均高于对照组。结论重庆地区妊娠妇女弓形体、巨细胞感染率处于一般水平,梅毒感染率较高,不良妊娠结局与TORCH感染有关,进行TORCH检查对优生优育有重要意义。OBJECTIVE To investigate the prevalence of TORCH infections in the planned pregnancy women in Chongqing so as to provide guidance for the first level intervention to the prevention of birth defects .METHODS From Apr 2013 to Dec 2013 ,a total of 11 953 women who conformed to the family planning policy and planned to be pregnant in three months were extracted for questionnaire survey by using proportionally stratified multi‐stage random sampling method .The venous blood specimens were collected ,and the TORCH specific antibodies were detected by means of ELISA .RESULTS Among the 11 953 planned pregnancy women ,the incidence of cytomega‐lovirus infection was 0 .38% ,the incidence of toxoplasma infection was 0 .59% ,and the incidence of syphilis infec‐tion was 0 .89% ;the incidence of cytomegalovirus infection was the highest （1 .19% ） in the southeastern Chongqing （6 countries） ,the incidence of toxoplasma infection was the highest （0 .94% ） in the＆#39;one hour economic zone＆#39;（22 countries） ,and the incidence of syphilis infection was the lowest （0 .23% ） in the northeastern Chongqing （11 countries ） .The incidence of syphilis infection was increased with the age ,the incidence of toxoplasma infec‐tion was increased with the education level ,and the incidence of syphilis infection was decreased with the rise of education level .The incidence of toxoplasma infection varied in the women with different occupations ,and it was the highest in the civil servants （1 .06% ） ,the lowest in the farmers （0 .37% ） .The positive rates of cytomegalov‐irus ,toxoplasma ,and syphilis were higher in the women with history of adverse pregnancy outcomes than in the women of the control group .CONCLUSION The incidence of toxoplasma or cytomegalovirus infection is on the av‐erage level of the planned pregnancy women in Chongqing ,and the incidence of syphilis infection is relatively high . The adverse pregnancy outcomes are associated with the TORCH infection .The examination of TORCH ma

关 键 词：计划妊娠 TORCH感染 现况调查 

分 类 号：R181.32[医药卫生—流行病学]