高血压病患者脉象参数与血压变异性的相关研究  

Relevant Study on Relationship Between Pulse Condition and Blood Pressure Variability in Patients with Essential Hypertension

作　　者：魏世超[1,2] 张林香[3] 郑星宇[1,2] 薛飞龙[2] 骆杰伟[1,2] 郭苗苗[2] 孟晓嵘[1,2] 黄昉萌[1,2] 

机构地区：[1]福建医科大学省立临床学院,福建福州350001 [2]福建省立医院,福建福州350001 [3]龙岩市第二医院,福建龙岩364000

出　　处：《中医临床研究》2015年第30期23-28,共6页Clinical Journal Of Chinese Medicine

基　　金：福建省科技计划重点项目(2014Y0007);福建省中医药科研项目(wzrk201314)

摘　　要：目的:探讨高血压病(EH)脉象参数与血压变异性(BPV)的相关性。方法:收集高血压病130例的脉象参数(DDMX-100脉象仪)及24 h动态血压数据,计算BPV。结果:偏相关分析显示,调整年龄、体重指数等影响因素后,24 h SBP与h3、h3/h1、h4/h1、W1、As、Ad呈负相关,r分别-0.294、-0.327、-0.382、-0.348、-0.177、-0.289(P<0.05),而h5/h1与24 h SBP、24 h DBP呈正相关,r分别为0.207、0.192(P<0.05);PP与h3、h3/h1、h4/h1、W1、As、Ad呈负相关,r分别为-0.322、-0.373、-0.385、-0.323、-0.218、-0.274(P<0.05);24 h SBPSD与h4/h1、Ad呈负相关(r=-0.264、-0.269,P<0.01);24 h SBPL与h3、h3/h1、h4/h1、W1、As、Ad呈负相关(r=-0.399、-0.380、-0.478、-0.385、-0.276、-0.428,P<0.01)。结论:血压变异性(BPV)影响了高血压病的脉象构成。Objective： To study and explore the correlation between pulse parameters and blood pressure variability（BPV） in essential hypertension（EH）. Methods： Data of Pulse parameters by DDMX-100 electropulsograph and 24-hour ambulatory blood pressures was collected from 130 cases, and blood pressure variability（BPV） was calculated accordingly. Results： Partial correlation analyses showed as follows： 24 h SBP（24 h mean systolic blood pressure） was negatively correlated with h3（tide wave height）, h3/h1（principal wave height）, h4（dicrotic notch height）/h1, W1（pulse diagram width above 1/3h1）, As（systole area） and Ad（diastole area）（respectively, r =-0.294,-0.327,-0.382,-0.348,-0.177,-0.289, P〈0.05）,while 24 h SBP, 24 h DBP（24 h mean diastolic blood pressure） was positively correlated with h5（repulse wave height） /h1（respectively, r = 0.207, 0.192, P〈0.05）. PP（Pulse pressure） was negatively correlated with h3, h3/h1, h4/h1, W1, As and Ad（respectively, r =-0.322,-0.373,-0.385,-0.323,-0.218,-0.274, P〈0.05）. 24 h SBPSD（24h SBP Standard deviation） was negatively correlated with h4/h1, As and Ad（respectively, r =-0.264, 0.269,P〈0.01）. 24 h SBPL（24h SBP load） was negatively correlated with h3, h3/h1, h4/h1, W1, As, Ad（respectively, r =-0.399,-0.380,-0.478,-0.385,-0.276,-0.428,P〈0.01）. Conclusion： Blood pressure variability（BPV） leads to pulse variety of EH.

关 键 词：高血压病 血压变异性 脉象 

分 类 号：R541.4[医药卫生—心血管疾病]