左卡尼汀对新生儿窒息后心肌损害的疗效观察  

Study on the effect of L-carnitin for myocardial injury in neonatal asphyxia

作　　者：黄铃沂[1,2] 朱慧[1,2] 刘佳华[2,3] 

机构地区：[1]福建省立医院重症医学五科,福州350001 [2]福建医科大学省立临床医学院,福州350001 [3]福建省立医院妇产科,福州350001

出　　处：《创伤与急诊电子杂志》2015年第4期49-50,48,共3页Journal of Trauma and Emergency(Electronic Version)

摘　　要：目的观察左卡尼汀治疗新生儿窒息后心肌损害的疗效。方法将70例新生儿窒息后心肌损害患儿随机分为对照组及治疗组,两组均给予常规治疗,治疗组加用左卡尼汀治疗,每日0.1g/kg微量泵泵入、1日1次,连续7天,观察两组患儿的疗效、肌酸激酶同工酶(CK-MB)及肌钙蛋白(TnI)水平。结果治疗组患儿总有效率显著高于对照组,CK-MB及TnI下降水平显著高于对照组。结论左卡尼汀治疗新生儿窒息后心肌损害疗效显著。Objective To observe the efficacy of L-Carnitin on myocardial injury in newborns with asphyxia. Method Seventy cases of myocardial damage in newborns with asphyxia were randomly devided into control group and treatment group：both were given routine management,while treatment group were administered L-carnitin（0.1g/kg,ivgtt,Qdx7）. Result The total effective rate of treatment group was higher than that of control group（P〈0.05）,the levels of CK-MB and TnI of treatment group were significantly decreased after therapy（P〈0.05）. Conclusion It is effective and safe to use L-carnitin in myocardial damage caused by neonatal asphyxia.

关 键 词：左卡尼汀 新生儿窒息 心肌损害 

分 类 号：R722.12[医药卫生—儿科]