无创呼吸机辅助治疗老年慢性阻塞性肺疾病合并呼吸衰竭的临床效果研究  

Clinical Effect of Non- invasive Ventilator in the Adjuvant Treatment of Aged Chronic Obstructive Pulmonary Disease Patients Complicated with Respiratory Failure

作　　者：万小兵[1] 陈宇洁[1] 陆海英[1] 

机构地区：[1]四川省第四人民医院呼吸内科,四川省成都市610016

出　　处：《实用心脑肺血管病杂志》2015年第9期96-98,共3页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：四川省科技厅科技支撑项目(2015SZ0183)

摘　　要：目的探讨无创呼吸机辅助治疗老年慢性阻塞性肺疾病合并呼吸衰竭的临床效果。方法选取2013年7月—2014年11月四川省第四人民医院呼吸内科收治的80例老年慢性阻塞性肺疾病合并呼吸衰竭患者,按照随机数字表法分为对照组和观察组,每组40例。两组患者均给予常规治疗,观察组患者在常规治疗基础上联合无创呼吸机辅助治疗。比较两组患者治疗前后pH值、动脉血二氧化碳分压(PaCO2)、动脉血氧分压(PaO2)、血氧饱和度(SaO2)、心率(HR)与呼吸频率(RR),记录并比较两组患者住院时间、并发症发生率。结果治疗前两组患者pH值、PaCO2、PaO2、SaO2、HR、RR比较,差异无统计学意义(P>0.05);治疗后,观察组患者pH值、PaO2、SaO2均高于对照组,PaCO2、HR、RR均低于对照组(P<0.05)。对照组患者住院时间为(11.7±3.9)d,长于观察组的(9.1±3.4)d(P<0.05);观察组患者并发症发生率为5.0%,低于对照组的27.5%(P<0.05)。结论无创呼吸机辅助治疗老年慢性阻塞性肺疾病合并呼吸衰竭的临床效果确切,有利于缩短患者住院时间且并发症发生率低。Objective To investigate the clinical effect of non- invasive ventilator in the adjuvant treatment of aged chronic obstructive pulmonary disease patients complicated with respiratory failure. Methods From July 2013 to November2014,a total of 80 aged chronic obstructive pulmonary disease patients complicated with respiratory failure were selected in the Department of Respiratory Medicine,the Fourth People＇ s Hospital of Sichuan Province, and they were randomly divided into control group and observation group,each of 40 cases. Patients of both groups received conventional treatment,while patients of observation group received extra non- invasive ventilator for assisted ventilation based on conventional treatment. Before and after treatment,pH,PaCO2,PaO2,SaO2,HR and RR were compared between the two groups,and hospital stays and incidence of adverse reactions were recorded. Results No statistically significant differences of pH,PaCO2,PaO2,SaO2,HR or RR was found between the two groups before treatment（ P〉0. 05）; after treatment, pH, PaO2 and SaO2 of observation group were statistically significantly higher than those of control group, while PaCO2,HR and RR of observation group were statistically significantly lower than those of control group（ P〈0. 05）. The hospital stays of observation group was（ 9. 1 ± 3. 4） days,was statistically significantly shorter than that of control group of（ 11. 7 ± 3. 9） days（ P〈0. 05）; the incidence of adverse reactions of observation group was 5. 0%, was statistically significantly lower than that of control group of 27. 5%（ P〈0. 05）.Conclusion Non- invasive ventilator has certain clinical effect in the adjuvant treatment of aged chronic obstructive pulmonary disease patients complicated with respiratory failure, is helpful to shorten the hospital stays, and is with lower incidence of adverse reactions.

关 键 词：肺疾病 慢性阻塞性 老年人 通气机 机械 治疗结果 

分 类 号：R563.9[医药卫生—呼吸系统]