磁性纳米四氧化三铁在生物医学中的应用  

Applications of Magnetic Fe_3O_4 Nanoparticles in Biomedical Field

作　　者：康路[1] 胡平[1] 杨军[1] 王华[2] 杨帆[1] 杜金晶[1] 杨占林[1] 

机构地区：[1]西安建筑科技大学冶金工程学院,西安710055 [2]西安电炉研究所有限公司,西安710061

出　　处：《材料导报》2015年第21期132-136,144,共6页Materials Reports

基　　金：国家自然科学基金(51404181)

摘　　要：近年来,由于磁性纳米粒子在实际应用中发挥越来越重要的作用,有关磁性纳米粒子的应用受到科学界广泛关注,特别是生物医学领域。由于磁性纳米Fe_3O_4粒子制作简单且晶体对细胞无毒,在生物医药领域大量应用,磁性纳米Fe_3O_4粒子主要通过表面包覆成为免疫磁性微球进行使用。简述了磁性纳米Fe_3O_4粒子的制备方法,重点综述了近些年磁性纳米Fe_3O_4粒子在生物医学上的应用,包括磁共振成像技术、磁分离技术、靶向药物载体技术、肿瘤热疗技术、造影剂技术,并且阐述了磁性纳米Fe_3O_4粒子的发展前景。In recent years, due to the more and more important role that magnetic nanoparticles played in the practical application, their application is widely concerned, especially in the biomedical field. Magnetic Fe3O4 nanoparticles are widely used in the biomedical field because they are made simple and crystal-toxic to cells. And they become coated primarily by immune magnetic beads for use. The preparation methods of magnetic Fe3O4 nanoparticles are introduced, and the applications of magnetic nanoparticles in biomedicine in recent years are reviewed, including： magnetic resonance imaging technology, magnetic separation technology, targeting drug carrier technology, tumor hyper thermia technology, and contrast agent technology. And the prospects Fe3O4 magnetic nanoparticles is explained.

关 键 词：磁性纳米粒子 FE3O4 免疫磁性微球 生物医药 

分 类 号：TB383[一般工业技术—材料科学与工程]