艾滋病合并乙型肝炎病毒、丙型肝炎病毒和梅毒感染分析  

Analysis of co-infection of hepatitis B,hepatitis C virus and syphilis in AIDS patients

作　　者：潘虹[1] 毛尚根 刘芳宇[1] 晏火兰 文奇[1] 

机构地区：[1]新余市疾病预防控制中心,江西新余338000

出　　处：《中国卫生检验杂志》2015年第21期3705-3706,共2页Chinese Journal of Health Laboratory Technology

基　　金：新余市科技攻关项目(20133090841)

摘　　要：目的了解AIDS合并感染乙肝(HBV)、丙肝(HCV)及梅毒(TP)的状况,为AIDS的防治提供实验依据。方法采集新余市134例AIDS患者的血清,通过酶联免疫吸附实验检测血清中的乙肝表面抗原和抗体、丙肝和梅毒抗体。结果在134例AIDS患者中,合并感染HBV 35例(26.12%),感染HCV 6例(4.48%),感染TP 18例(13.43%);同时合并HBV、HCV感染3例(2.24%),合并HBV、TP感染5例(3.73%),合并HCV、TP感染1例(0.75%),未发现四重重叠感染。多重感染者与单纯HIV感染者的CD4+T细胞值比较,差异具有统计学意义(P<0.05)。结论在本市的AIDS患者中,HBV、HCV和TP都有较高的感染率,多重感染者的免疫力与单纯HIV感染者差异显著。多重感染的AIDS患者应针对性用药。Objective To survey the co- infection epidemic of HBV,HCV and TP in AIDS patient,to provide experimental evidence for AIDS prevention. Methods The serum samples of 134 AIDS patients in Xinyu were collected. With the assay of enzyme- linked immunosorbent,the HBs Ag,HCV and TP antibodies in the serum samples were detected. Results In 134 patients with AIDS,35 patients（ 26. 12%） were infected with hepatitis B virus,6 patients（ 4. 48%） with HCV and 18 patients（ 13. 43%） with TP,3 patients（ 2. 24%） with HBV and HCV,5 patients（ 3. 73%） with HBV and TP,and 1 patients（ 0. 75%） with HCV and TP. Four co- infection was not found. The difference between the CD4＋T cell number of multi- infected person and single HIV- infected patient had statistical significance（ P〈 0. 05）. Conclusion There are highly infectious rates of HBV,HCV and TP in AIDS patients in Xinyu. The immune of multi- infected patients and single HIV- infected were significantly different. Drugs of multi- infected patients should be targeted.

关 键 词：艾滋病 乙型肝炎 丙型肝炎 梅毒 合并感染 CD4+T细胞 

分 类 号：R181.8[医药卫生—流行病学]