2007-2013年云南大理地区广州管圆线虫病病例分析及流行现状  

Case analysis and prevalence of angiostrongyliasis cantonensis in Dali administrative distract from 2007 to 2013

作　　者：姚素华 武有聪[2] 李芹翠 刘平 

机构地区：[1]大理州人民医院神经内科,云南大理671000 [2]大理学院基础医学院病原生物学综合实验室,云南大理671000

出　　处：《热带医学杂志》2015年第10期1413-1417,共5页Journal of Tropical Medicine

摘　　要：目的分析和总结大理地区广州管圆线虫病的临床特点及流行现状。方法通过查阅有关广州管圆线虫病的文献资料,结合本院接诊病例,总结了2007-2013年大理地区广州管圆线虫病的病例特点,并从广州管圆线虫的自然疫源地、中间宿主及终末宿主等几个方面分析大理地区广州管圆线虫病的流行现状及常用诊断技术。结果大理地区共有2次广州管圆线虫病流行,多次散发,累计报告77例病例,男性41例,女性36例,主要以白族(占68.8%)为主;临床以头痛和脑脊液中嗜酸性粒细胞增高为主,83.1%患者有进食生食史。结论大理地区广州管圆线虫病得到了控制,但仍在一定范围内流行,其主要通过进食生螺肉而感染。接触史和脑脊液中嗜酸性粒细胞增高仍是目前广州管圆线虫病诊断的主要依据,分子生物学诊断尚待进一步研究。Objective To analyze the clinical properties and prevalence of angiostrongyliasis cantonensis in Dali administrative district from 2007 to 2013. Methods The prevalence status and commonly used diagnostic techniques of angiostrongyliasis cantonensis were studied by literature review and cases report analysis,focusing on several aspects including natural epidemic focus,intermediate hosts and final hosts of Angiostrongylus cantonensis. Results Up to now,2 outbreaks and a number of sporadic cases have been occurred in Dali administrative district,and there were 77 clinical cases in total. Among them,41 were male,36 female,Bai population was 68.8%,and 83.1% of patients with a history of eating raw food. The patients almost experienced headache and increased eosinophils in cerebrospinal fluid. Conclusion Angiostrongylus cantonensis infection was mainly through eating raw snail and has been under control in Dali district. Diagnosis of angiostrongyliasis cantonensis mainly depended on a combination of clinical manifestation,epidemiological contact and eosinophil numeration in cerebrospinal fluid.Molecular approaches that target genetic sequence of A. cantonensisis needed to be further studied.

关 键 词：广州管圆线虫病 流行 大理 

分 类 号：R532.1[医药卫生—内科学]