重症艰难梭菌感染者诊治研究进展  

Advances in the diagnosis and treatment of severe infection of Clostridium difficile

作　　者：熊号峰[1] 刘景院[1] 李兴旺[2] 

机构地区：[1]首都医科大学附属北京地坛医院危重症内科部,北京100015 [2]首都医科大学附属北京地坛医院感染中心,北京100015

出　　处：《中华实验和临床感染病杂志（电子版）》2015年第5期37-40,共4页Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)

基　　金：国家"十二五"科技重大专项(No.2012ZX10004301-002);首都医科大学重大传染病防治协同创新中心资助项目(No.3500-11431502)

摘　　要：艰难梭菌感染(CDI)可引起大肠内膜炎,其主要症状可有不同程度的腹泻、发热、腹痛和便血,也可引起败血症、肠穿孔及腹腔感染。重症患者需要接受抗菌药物、支持治疗以及密切监护,部分患者可能需要接受外科手术治疗。其他替代治疗方案目前正在研究中,包括益生菌、粪便灌肠以及其他一些抗菌药物的治疗。Clostridium dififcile infection （CDI） could cause meningitis of the large intestine, the main symptoms may have different degrees of diarrhea, fever, abdominal pain and blood in the stool; it could also cause sepsis, intestinal perforation and abdominal infection. Critical patient needs antibiotics, supportive care and close monitoring, some patients may need to receive surgery. Other alternative treatment options are currently being studied, including probiotics, fecal enemas and other antibiotics.

关 键 词：艰难梭菌 感染 危重症 治疗 

分 类 号：R516[医药卫生—内科学]