急进高海拔地区血氧饱和度和心率变化的研究  

Research of raccelerated plateau on the change of blood oxygen saturation and heart rate

作　　者：彭翠翠[1] 王劲[1] 金婕[1] 钟前进[2] 童卫东[3] 周林[4] 

机构地区：[1]第三军医大学大坪医院野战外科研究所血液内科,重庆400042 [2]第三军医大学大坪医院野战外科研究所心血管外科,重庆400042 [3]第三军医大学大坪医院野战外科研究所胃肠外科,重庆400042 [4]第三军医大学大坪医院野战外科研究所心血管内科,重庆400042

出　　处：《重庆医学》2015年第33期4609-4610,4614,共3页Chongqing medicine

基　　金：国家重点基础研究发展计划(973计划)课题(2011CB964701)

摘　　要：目的观察平原人员急进高海拔地区后血氧饱和度、心率的变化,为高原地区医学救援提供参考。方法受试者从平原地区（海拔400m）出发,出发前测定血氧饱和度、心率,乘飞机到达海拔4 300m地区时测定血氧饱和度、心率;之后乘车到达海拔3 200m目的地后动态连续监测血氧饱和度、心率,分别在到达后第1~7天测定血氧饱和度、心率;受试者在海拔3 200m地区适应1周后乘车复返海拔4 300m地区,再次测定血氧饱和度、心率。结果进入海拔4 300、3 200m地区后血氧饱和度明显下降,与平原地区血氧饱和度差异有统计学意义（P〈0.05）。进入海拔3 200m地区后第6、7天血氧饱和度与第1天比较,差异有统计学意义（P〈0.05）。受试者乘飞机到达海拔4 300 m地区和乘车复返海拔4 300 m地区的氧饱和度差异有统计学意义（P〈0.05）,心率间差异无统计学意义（P〉0.05）。结论随着海拔的增高,动脉血氧饱和度随之下降,平原人员急进海拔3 200m地区第6天能初步适应,在较低海拔地区短时间适应后再进入高海拔地区人体能更好地适应。Objective To investigate the changes of blood oxygen saturation and heart rate after urgently going to high-altitude area,so as to provide a reference for medical rescue in high-altitude area.Methods Subjects left from the plain area with an altitude of 400 m.Blood oxygen saturation and heart rate were measured before departure and after reaching 4 300 maltitude region.Then the subjects were taken to the destination with an altitude of 3 200 m,at which they received a dynamic continuous monitoring of blood oxygen saturation/heart rate at the 1st day,2nd day,3rd day,4th day,5th day,6th day,7th day after arrival.After adapting to the environment in 3 200 maltitude area for 1week,subjects were taken to the 4 300 maltitude region,at which they were remeasured blood oxygen saturation and heart rate.Results After entering the areas of 4 300 maltitude and 3 200 maltitude,the blood oxygen saturation was significantly decreased compared with that in plain area（P〈0.05）.The blood oxygen saturation at the6 th and 7th day after entering 3 200 maltitude area was statistically different when compared with that at the 1st day（P〈0.05）.The blood oxygen saturation had statistical difference between reaching at 4 300 maltitude area for the first time and re-entering 4300 maltitude area,while the heart rate had no statistical difference（P〉0.05）.Conclusion The arterial oxygen saturation was decreased with the increase of altitude;the people living in plain areas can preliminarily adapt to the environment at 6th day after reaching 3200 maltitude regions;people can better adapt to the high-altitude environment by shortly living in lower-altitude areas before re-entering high-altitude areas.

关 键 词：心率 高海拔 血氧饱和度 急进高原 高原适应 

分 类 号：R594.3[医药卫生—内科学]