大气污染致慢性呼吸道疾病机制研究  

MECHANISM OF CHRONIC RESPIRATORY DISEASES CAUSED BY AIR POLLUTION

作　　者：林子英[1] 任妮娜[1] 刘刚[1] 

机构地区：[1]广东医学院临床医学研究中心,广东湛江524001

出　　处：《现代医院》2015年第1期9-12,共4页Modern Hospitals

基　　金：国家自然科学基金项目(编号:81172615);广东医学院科技创新资助项目(编号:STIF201109)

摘　　要：许多证据表明大气污染与慢性呼吸道疾病有关,其中以颗粒物的影响最为人们所关注。无论是儿童还是成人,呼吸系统疾病与大气污染程度都密切相关,这也是当前研究的热点。大气污染对呼吸系统疾病的影响机制包括氧化应激、炎症反应、遗传损伤等;本文就大气颗粒物PM2.5导致慢性呼吸道疾病发病机制的最新进展进行综述。Lots of evidence show a correlation between air pollution and chronic respiratory diseases,of which the effect of particulate matter is the most concerned. It is the current research hotspot that respiratory diseases in both children and adults are closely related with atmospheric pollution levels. The influence mechanisms of atmospheric pollution on respiratory diseases include oxidative stress,inflammation,genetic damage,etc. This paper made a review of the latest advances s on the pathogenesis of chronic respiratory diseases caused by atmospheric particulates PM2. 5.

关 键 词：大气颗粒物 PM2.5氧化应激 慢性炎症 呼吸系统疾病 

分 类 号：R473.5[医药卫生—护理学]