毒害艾美耳球虫感染对雏鸡免疫器官指数及主要器官病理形态变化的影响  

Effects of E.necatrix on Immune Organ Index and Main Organ Pathological Changes of Chickens

作　　者：刘文超[1] 马春霞[1,2] 赵靓[1] 周英[1] 郑世民[1] 

机构地区：[1]东北农业大学动物医学学院,黑龙江哈尔滨150030 [2]广西兽医研究所,广西南宁530001

出　　处：《中国家禽》2015年第21期26-31,共6页China Poultry

基　　金：黑龙江省教育厅项目(12531015)

摘　　要：为探究毒害艾美耳球虫感染对雏鸡免疫器官指数及主要器官组织病理变化的影响,将90只14日龄雏鸡随机分为3组,即毒害艾美耳球虫二次感染组(Ⅰ组)、一次感染组(Ⅱ组)和对照组(C组),通过对胸腺、法氏囊、脾脏、盲肠扁桃体器官指数的测定和主要器官病理变化的观察,并对两者的相关性进行了系统分析。结果发现:毒害艾美耳球虫一次感染雏鸡后,其胸腺指数降低;而法氏囊、脾脏和盲肠扁桃体器官指数升高。毒害艾美耳球虫两次感染雏鸡后,其中枢免疫器官指数高于毒害艾美耳球虫一次感染雏鸡;但外周免疫器官指数低于一次感染雏鸡。病理形态变化检查发现,雏鸡一次感染毒害艾美耳球虫后,脾脏、盲肠扁桃体微肿胀,胸腺质地变软、颜色变淡,点状出血,小肠前段肿胀,黏膜充血;镜下可见实质细胞明显肿大,部分细胞核浓缩、深染,部分细胞崩解消失,炎性细胞、红细胞和杯状细胞增多。本研究结果为进一步探讨鸡球虫的致病机制提供了重要参考依据。In order to study the effects of E. necatrix on immune organ index and the main organ pathological changes of chickens,ninety 14-day-age chickens were randomly divided into three groups,which were the secondary infection with E. necatrix （group Ⅰ） ,initial infection with E. necatrix （group Ⅱ） ,and control group （C）. A systemic analysis of the correlation was made, after we determined the index of thymus, bursa of Fabricius, spleen, cecal tonsil and observed the pathologic changes of the major organs,the results showed that index of thymus reduced and the index of bursa of fabricius,spleen, cecal tonsil increased after the chickens were initial infected with E. necatrix. After the chickens were secondary infected with E. necatrix, central immune organ index were higher than group Ⅱ ;but peripheral immune organ index were lower than group Ⅰ. It could be found from checking the changes of the pathological, after initial infected with E. necatrix, The spleen, cecal tonsil micro swelling, the texture of the thymus got softer, color faded, petechial hemorrhages;under microscope, the parenchymal cells clearly swollen,part of the nucleus concentrated, anachromasis, part of cells disintegrate disappear, inflammatory ceils, red blood cells and goblet cells increased. The study provided significant evidence for the pathogenic mechanism of chicken coccidiosis.

关 键 词：毒害艾美耳球虫 雏鸡 器官指数 病理形态变化 

分 类 号：S858.31[农业科学—临床兽医学]