穿山龙乙醇动态提取工艺优化研究  

Alcohol dynamic extraction of Dioscorea nipponica Makino

作　　者：曹颂 王蕾[1] 周培培[1] 蒋建兰[1] 

机构地区：[1]天津市生物与制药工程重点实验室天津大学化工学院制药工程系,天津300072

出　　处：《现代化工》2015年第11期81-85,共5页Modern Chemical Industry

摘　　要：优化穿山龙乙醇动态连续提取工艺。通过单因素试验对乙醇浓度、液料比、回流速度、回流时间等进行了筛选,利用Central Composite Design响应面设计优化试验,以干浸膏得率和薯蓣皂苷含量作为评价指标,利用响应面对干浸膏得率进行了分析,支持向量回归(SVR)对薯蓣皂苷含量进行了分析。根据单因素试验结果确定了各因素对提取效果的影响,并确定了相应工艺范围。The dynamic alcohol extraction of Dioscorea nipponica Makino is optimized in this study. The effects of ethanol concentration, solvent/solid ratio, reflux time and reflux speed on the yield of dry extractant and dioscin are studied. A Central Composite Design response surface methodology is employed. Support Vector Regression Algorithm is used to analyze the dioscin content. The extracting effect and process parameters can also be evaluated by single factor experiment.

关 键 词：穿山龙 醇提 响应面 支持向量回归 干浸膏得率 薯蓣皂苷 

分 类 号：R93[医药卫生—生药学]