皮下修剪术与搔刮术治疗腋臭的临床疗效Meta分析  

Clinical efficacy of subcutaneous pruning and curettage treatment for axillary osmidrosis: Meta analysis

作　　者：陆思锭 殷国前[1] 潘新元[1] 彭鎏[1] 唐胜华[1] 陈子翔[1] 朱江英[1] 

机构地区：[1]广西医科大学第一附属医院整形美容外科,广西南宁530000

出　　处：《临床皮肤科杂志》2015年第12期829-834,共6页Journal of Clinical Dermatology

摘　　要：目的:对皮下修剪术与搔刮术两种手术方法治疗腋臭的疗效进行系统评价。方法:应用计算机检索相关文献数据库,收集国内外有关皮下修剪术及搔刮术治疗腋臭的随机对照试验研究。评价纳入研究的方法学质量并进行资料提取后,采用Rev Man 5.2软件进行Meta分析。结果:最终共纳入12个中文随机对照研究,共2 677侧腋臭部位,其中修剪组1 288侧,搔刮组1 389侧,Meta分析结果显示修剪术治愈率较搔刮术高(OR=4.00,P=0.004);且复发率比搔刮术低(OR=0.31,P<0.000 01)。修剪术与搔刮术有效率、血肿、感染、皮肤或皮瓣坏死、切口裂开、瘢痕发生率及总并发症比较,差异均无统计学意义(P>0.05)。结论:现有数据Meta分析表明,修剪术较搔刮术治疗腋臭具有治愈率高且复发率低的优势,安全可行。由于文献质量普遍不高,纳入样本量偏少,今后尚需进一步开展设计良好及方法学质量更高的随机对照试验。Objective： To systemically assess the effectiveness of subcutaneous pruning and curettage for the treatment of axillary osmidrosis. Methods： The domestic and foreign literatures were retrieved by computer to collect all the randomized controlled clinieM trims （RCT） on subcutaneous pruning and subcutaneous curettage for the treatment of axillary osmidrosis. The quality of the included studies was evaluated, and Meta-analysis was performed using RevMan 5.2 software. Results： A total of 12 Chinese RCT were included, they were 1 288 sites of axillae treated with subcutaneous pruning, and 1 389 sites of axillae treated with subcutaneous curettage. The results of the Meta-anMysis indicated that the curative rate Of subcuta- neous pruning was obviously superior to that of subcutaneous curettage（OR=4.00, P=0.004）, and the recurrence rate was low- er than that of subcutaneous curettage （OR=0.31, P〈0.000 01）. The differences of effective rate, complication rates （hematoma formation, infection, necrosis of the skin or flap, wound dehiscence and scar formation） between the two groups were not sta- tistically significant（P〉0.05）. Conclusion： Compared with subcutaneous curettage, subcutaneous pruning for the treatment of axillary osmidrosis has the advantages of high cure rate and low recurrence rate, and safe and feasible. Due to the small sample size and low quality of the included studies, further well-designed RCT should be performed.

关 键 词：腋臭 皮下修剪术 皮下搔刮术 临床随机对照试验 META分析 

分 类 号：R758.741[医药卫生—皮肤病学与性病学]