脑络欣通对后循环缺血支架术后再狭窄预防作用研究  

Study on prevention of restenosis after cerebral circulation ischemia stent implantation

作　　者：马守亮[1] 杨文明[1] 王艳昕[1] 吴云虎[1] 侯志峰[1] 蔡永亮[1] 谭大宏 侯玉宝[2] 

机构地区：[1]安徽中医药大学第一附属医院,安徽合肥230031 [2]安徽省怀远县中医院,安徽怀远233400

出　　处：《中医药临床杂志》2015年第10期1421-1423,共3页Clinical Journal of Traditional Chinese Medicine

基　　金：国家科技部支撑计划项目(编号:2012BAI26B02);安徽省科技攻关项目(编号:11010402167);康缘中医药科技创新基金资助项目(编号:KYCX201010);安徽中医药大学青年基金项目(编号:2014Fy011)

摘　　要：目的:观察脑络欣通对后循环缺血支架术后血浆黏度、纤维蛋白原、血管支架部位血管直径变化,阐明脑络欣通对后循环缺血支架术后患者能否提高临床疗效及手术成功率,减少并发症的发生。探讨脑络欣通对后循环缺血支架术后再狭窄预防作用机制。方法:采用完全随机设计方法,将符合纳入标准的60例患者,按照随机数字表方法,随机分为治疗组30例和对照组30例。结果:手术后治疗组分别于3个月、6个月、1年患者行脑血管造影、并检测血浆黏度、纤维蛋白原观察指标。结果:治疗组在动脉狭窄率、血浆黏度、纤维蛋白原等指标作用优于对照组(P<0.05)。结论:脑络欣通对后循环缺血支架术后再狭窄预防作用效果显著,脑络欣能预防动脉内支架再狭窄,提高手术的成功率。Objective：Observation Naoluoxintong of changes in vessel diameter portion of the stent, to clarify posterior circulation ischemia stent plasma viscosity, fibrinogen, the clinical efficacy and procedural success rate Naoluoxintong of posterior circulation ischemia in patients after stent can improve and reduce complications. Discussing Naoluoxintong of posterior circulation ischemia stent restenosis prevention mechanism. Methods：A completely randomized design method, met the inclusion criteria, 60 patients, according to the random number table method, 30 cases were randomly divided into treatment group and the control group of 30 patients. Results：After surgery group were 3 months, 6 months, 1 year un- derwent cerebral angiography and plasma viscosity and fibrinogen were observed. Results：The treatment group than the control group （P〈0.05） in the role of indicators artery stenosis rate, plasma viscosity, fibrinogen. Conclusion ： Naoluoxintong of posterior circulation ischemia stent restenosis prevention effect is remarkable, Naoluo can prevent arterial restenosis, improve the success rate of surgery.

关 键 词：脑络欣通 后循环缺血 支架术后再狭窄 预防作用 

分 类 号：R259[医药卫生—中西医结合]