米非司酮预防成年女性药物流产后并发妇科炎症的临床疗效研究  

Clinical efficacy of mifepristone to prevent gynecological inflammation in adult female after medical abortion

作　　者：齐林君 钱莉莉[2] 陈红萍[3] 

机构地区：[1]天台县苍山医院妇产科,浙江台州317206 [2]浙江大学附属妇产科医院妇产科,杭州310000 [3]天台县妇幼保健所妇产科,浙江台州317200

出　　处：《中国性科学》2015年第11期57-59,共3页Chinese Journal of Human Sexuality

摘　　要：目的:探讨米非司酮在预防成年女性药物流产后并发妇科炎症中的临床疗效。方法:选取2013年3月至2014年3月期间在我院进行药物流产的成年女性53例,随机分为观察组(n=27)和对照组(n=26),在米非司酮联合米索前列醇进行药物流产后,观察组继续服用米非司酮对患者进行早期药物干预,观察临床疗效。结果:在药物流产2周后,观察组尿人体绒毛膜促性腺激素(HCG)水平为(65.87±13.49)IU/L,对照组为(66.94±12.87)IU/L,与流产前有显著性差异,两组间无差异,经B超检查确定所有女性流产完全。观察组在米非司酮治疗后,宫颈炎有1例,阴道炎1例,而阴道出血及颈柱状上皮异位均为0例,与对照组相比有显著性差异(P<0.05)。结论:成年女性药物流产后及早用米非司酮干预治疗,可以明显减少药物流产合并妇科炎症的发生,改善患者健康状况及生活质量。Objectives： To investigate the clinical efficacy of mifepristone to prevent gynecological inflam- mation in adult female after medical abortion. Methods： 53 adult female received medical abortion in our hospital from March 2013 to March 2014 were selected and divided into observation group （n = 27） and control group （n = 26） randomly. After the medical abortion using mifepristone and misoprostol, the observation group took the mife- pristone continually to observe the clinical efficacy. Results： Two weeks after the medical abortion, the urine HCG average of observation group and control group was （65.87 ± 13.49） IU/L and （66.94 ± 12.87） IU/L respective- ly. Compared with the average before medical abortion, there was significant difference but there was no difference between the two groups. All adult female had done complete medical abortion confirmed by B - ultrasonic wave. Af- ter treatment of mifepristone, observation group had one case of cervicitis, one case of vaginitis and no vaginal bleeding and cervical erosion. Compared with control group, there was significant difference （P 〈 0. 05）. Conclu- sion： Taking mifepristone after medical abortion can obviously reduce the combined gynecological inflammation of a- dult female after medical abortion, which can significantly improve their health conditions and life quality.

关 键 词：米非司酮 成年女性 药物流产 妇科炎症 

分 类 号：R711.31[医药卫生—妇产科学]