Electron irradiation effects of radiochromic PCDA vesicle gel dosimeters  

作　　者：孙鹏 傅玉川 胡娟 李磊 王潇 黄玮 蒋波 

机构地区：[1]Department of Mathematics and Physics, Officers College of PAP [2]National Engineering Research Center for Biomaterials, Sichuan University [3]Radiation Physics Technique Center, West China Hospital [4]Radiotherapy Department, The Fifth People’s Hospital of Chengdu [5]Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics

出　　处：《Nuclear Science and Techniques》2015年第5期33-38,共6页核技术（英文）

基　　金：Supported by National Natural Science Foundation of China(No.81301934);the Science and Technology Development Foundation of China Academy of Engineering Physics(No.2013B0301035)

摘　　要：The gel dosimeter has the uniquely capacity in recording radiation dose distribution in three dimensions(3D), which has the specific advantages in dosimetry measurements where steep dose gradients exist. In this study, a novel radiochromic gel dosimeter was developed by dispersing nanovesicles self-assembled by 10,12-pentacosadiynoic acid(PCDA) into the tissue equivalence gel matrix. The characteristics of radiochromic PCDA vesicle gel dosimeters were evaluated. Results indicate that these radiochromic gel dosimeters have good linear response to 1.7 Me V electron beam irradiation in the dose range of 0.32–6.36 k Gy. In addition,the radiochromic gel dosimeters overcome the limitations of the existing gel dosimeters such as diffusion effect,post-radiation effect, and poor forming ability. Hence, the radiochromic PCDA vesicle gel dosimeters developed could be generally applied to 3D dose distribution measurement with optical readout.The gel dosimeter has the uniquely capacity in recording radiation dose distribution in three dimensions（3D）, which has the specific advantages in dosimetry measurements where steep dose gradients exist. In this study, a novel radiochromic gel dosimeter was developed by dispersing nanovesicles self-assembled by 10,12-pentacosadiynoic acid（PCDA） into the tissue equivalence gel matrix. The characteristics of radiochromic PCDA vesicle gel dosimeters were evaluated. Results indicate that these radiochromic gel dosimeters have good linear response to 1.7 Me V electron beam irradiation in the dose range of 0.32–6.36 k Gy. In addition,the radiochromic gel dosimeters overcome the limitations of the existing gel dosimeters such as diffusion effect,post-radiation effect, and poor forming ability. Hence, the radiochromic PCDA vesicle gel dosimeters developed could be generally applied to 3D dose distribution measurement with optical readout.

关 键 词：辐射剂量分布 凝胶基质 剂量计 电子辐照效应 变色 剂量测量 形成能力 电子束照射 

分 类 号：R814.2[医药卫生—影像医学与核医学]