老年髋部骨折患者住院期间急性心肌梗死发生风险分析  

Risk of acute myocardial infarction during hospitalization in elderly patients with hip fracture

作　　者：孟康[1] 陈妍[2] 王虹[3] 曹沛鸿 何锦泉[3] 

机构地区：[1]首都医科大学附属北京安贞医院心内科,100029 [2]天津胸科医院心内科 [3]天津市天津医院骨科

出　　处：《中国医药》2015年第12期1746-1750,共5页China Medicine

摘　　要：目的探讨老年髋部骨折患者住院期间急性心肌梗死（AMI）的发生风险。方法纳入2010年10月至2013年10月天津市天津医院老年骨质疏松性髋部骨折患者（髋部骨折组）和同期非骨质疏松性非髋部骨折患者（非髋部骨折组）。比较2组患者住院期间AMI的发生率，分析骨折患者发生AMI的危险因素。结果髋部骨折组和非髋部骨折组各纳入患者315例，住院期间AMI的发生率髋部骨折组高于非髋部骨折组[8．3％（26／315）比2．5％（8／315）]，差异有统计学意义（P〈0．05）；AMI患者中非ST段抬高型心肌梗死比例高于ST段抬高型心肌梗死[67．6％（23／34）比32．4％（11／34）]，差异有统计学意义（P〈0．05）。校正年龄、性别、合并疾病等危险因素后，髋部骨折为骨折患者住院期间发生AMI的独立危险因素（比值比：3．605，95％置信区间：1．391～9．345，P=0．008）。结论髋部骨折是骨折患者住院期间发生AMI的独立危险因素。Objective To investigate the risk of acute myocardial intarction （AMI） during hospitalization in elderly patients with hip fracture. Methods Elderly Patients with osteoporotic hip fracture （ hip fracture group） and non-osteoporotic non hip fracture （non hip fracture group） from October 2010 to October 2013 were enrolled. The incidence of AMI were compared between groups, the risk factors of AMI during hospitalization in fracture patients were analyzed. Results There were 315 patients in each group. The incidence of AMI in hip fracture group was significantly higher than that in non-hip fracture group [8.3% （26/315） vs 2.5% （8/315） ] （P 〈 0. 05 ）; the proportion of non ST segment elevation myocardial infarction was higher than that of ST segment elevation myocardial infarction [67.6% （23/34）vs 32.4% （11/34）] （P 〈0. 05）. After adjustment of relative factors such as age, gender and combined disease, hip fracture was independent risk factor of AMI in fracture patients （OR = 3. 605, 95% CI： 1. 391-9. 345, P = 0. 008）. Conclusion Hip fracture is an independent risk factor of AMI during hospitalization in patients with fracture.

关 键 词：髋部骨折 急性心肌梗死 危险因素 

分 类 号：R683.3[医药卫生—骨科学]