江苏省南京市2012-2014年川崎病流行病学调查  

Epidemiological study of children with Kawasaki disease in Nanjing of Jiangsu Province from 2012 to 2014

作　　者：谈诚[1] 殷丝雨[1] 李喆倩[1] 任晓艳[1] 刘丽莎[1] 

机构地区：[1]南京医科大学附属南京儿童医院检验科,江苏省南京210008

出　　处：《中国基层医药》2015年第21期3249-3251,共3页Chinese Journal of Primary Medicine and Pharmacy

基　　金：江苏省南京市医学科技发展基金项目（YKK13131）

摘　　要：目的：了解南京市川崎病（KD）患儿的发病情况、分布、流行病学特征。方法采用回顾性方法对2012-2014年在南京市儿童医院就诊的 KD 患儿的临床资料进行流行病学分析。结果2012-2014年该院共报告 KD 患儿1446例，其中完全 KD 占78．5％，不完全 KD 占21．5％；男女之比为1．7241，发病季节以春夏为发病高峰；发病年龄最小1个月，最大14岁，其中1岁以下者占30．49％，5岁以下占89．56％，≥5岁占10．44％；发热1438例，占99．45％，结膜充血1347例，占93．15％，杨梅舌1060例，占73．32％，四肢末端改变748例，占51．76％，皮疹1086例，占75．08％，淋巴结肿大664例，占45．89％。发生冠状动脉并发症病例共131例，占9．05％，男女之比为3．021；复发病例14例，复发率0．97％。结论KD 在南京及周边地区是儿童较常见疾病，应提高临床医生对该病的认识，做到早期诊断和治疗，对减少该病的后遗症及降低死亡率至关重要。Objective To evaluate the incidence and epidemiologic characteristics of Kawasaki disease （KD）in Nanjing.Methods We reviewed the medical records and reports of all patients admitted to Nanjing Chil-dren′Hospital with KD diagnosed during 3 -year periods from 2012 to 2014.Results We studied 1 446 inpatients diagnosed with KD from 2012 to 2014.There were 1 135 cases（78.5%）with complete KD.The ratio of male to female was 1.7241.The disease occurred in all of the seasons,but the peak was from spring to summer.Age at onset ranged from 1 month to 14 years old,and the peak age group was 1 year old.Fever（99.45%）was the most common clinical symptom,followed by conjunctive congestion（93.15%）,rash（73.32%）,oral changes（51.76%）, extremities desquamate（75.08%）and lymphadenopathy（45.89%）.There were 131（9.05%）patients with coronary aneurysm,the ratio of male to female was 3.02  1.14 patients （0.97%）developed recurrent KD.Conclusion Patients with KD has become more and more in Nanjing,and clinical doctors should improve the understanding of KD. Early diagnosis and treatment is very important to reduce the sequelae and reduce the mortality of KD.

关 键 词：川崎病 流行病学研究 

分 类 号：R725.4[医药卫生—儿科] R181.3[医药卫生—临床医学]