无创呼吸机辅助通气治疗慢性阻塞性肺疾病合并呼吸衰竭临床体会  

Clinical experience of non-invasive mechanical ventilation in chronic obstructive pulmonary disease with respiratory failure

作　　者：施红伟[1] 姚炳荣[1] 徐爱明[1] 刘春峰[1] 徐朝晖[1] 

机构地区：[1]江苏省南通市如东县人民医院重症医学科,226400

出　　处：《齐齐哈尔医学院学报》2015年第30期4541-4542,共2页Journal of Qiqihar Medical University

摘　　要：目的观察无创呼吸机辅助通气治疗慢性阻塞性肺疾病合并呼吸衰竭的临床效果。方法选取2013年1月至2014年6月间入住我院的52例慢性阻塞性肺病(COPD)合并呼吸衰竭患者,随机分为两组,对照组给予吸痰、通畅气道、低流量持续吸氧、呼吸兴奋剂、抗感染、补液、营养支持等常规治疗,治疗组在常规治疗基础上,加用无创呼吸机辅助通气。比较两组患者治疗前后有效率、血气分析及肺功能变化情况。结果治疗组的总有效率为92.00%,显著高于对照组(χ2=6.166,P=0.02);治疗后治疗组在Pa O2、Pa CO2、血p H及肺功能方面均优于对照组。结论无创呼吸机辅助通气治疗可显著提高COPD合并呼吸衰竭患者氧分压,改善呼吸状况及肺功能。Objective To observe clinical results of the non-invasive mechanical ventilation in chronic obstructive pulmonary disease with respiratory failure. Methods Between January 2013 and June 2014,52 patients admitted to our hospital with chronic obstructive pulmonary disease（ COPD） and respiratory failure were randomly divided into two groups,a control group was given suction,unobstructed airway,low flow continued oxygen,respiratory stimulants,antibiotics,rehydration,nutritional support and other conventional treatment group on the basis of conventional therapy plus noninvasive mechanical ventilation. Two groups of patients before and after treatment efficiency,blood gas analysis and pulmonary function changes. Results The total effective rate of 92. 00 percent effective,significantly higher（ χ2= 6. 166,P = 0. 02）; the treatment group in Pa O2,Pa CO2,blood p H and lung function than the control group. Conclusions Noninvasive mechanical ventilation therapy can significantly improve COPD patients with respiratory failure,oxygen partial pressure; improve the respiratory conditions and lung function.

关 键 词：慢性阻塞性肺疾病 呼吸衰竭 无创通气 呼吸机 

分 类 号：R563[医药卫生—呼吸系统]