不同采收期对何首乌中二苯乙烯苷和蒽醌类成分含量的影响  

Effect of Harvest Seasons on Main Bioactive Constituents in Polygoni Multiflori Radix

作　　者：李帅锋[1] 郑传柱[1] 张丽[1] 姚卫峰[1] 兰才武 贺定翔 丁安伟[1] 

机构地区：[1]南京中医药大学江苏省中药资源产业化过程协同创新中心/中药资源产业化与方剂创新药物国家地方联合工程研究中心,江苏南京210023 [2]贵州昌昊中药发展有限公司,贵州凯里556000

出　　处：《中国现代中药》2015年第11期1177-1179,1183,共4页Modern Chinese Medicine

基　　金：国家"十二五"科技支撑计划项目(2011BAI13B04);贵州省中药现代化专项(黔科合中药字[2013]5059号);江苏省中药资源产业化过程协同创新中心重点项目(ZDXM-1-3);江办高校优势学科建设工程资助项目(ysxk-2014);江苏高校品牌专业建设工程资助项目(PPZY2015A070)

摘　　要：目的:研究不同采收期对何首乌药材中二苯乙烯苷以及蒽醌类成分含量的影响,为何首乌适宜采收期的确定提供科学依据。方法:通过HPLC测定来自贵州施秉县不同采收期样品中二苯乙烯苷和蒽醌类成分的含量,同时采用主成分分析法对不同采收期何首乌样品质量进行综合评价。结果:不同采收期何首乌样品中二苯乙烯苷含量由高到低依次为:9月份>10月份>8月份>11月份>12月份>1月份。结合型蒽醌含量在9月份达到峰值,随后随时间推移而降低。主成分分析结果显示:不同采收期何首乌样品综合评价指数9、10月份较高。结论:9、10月份为何首乌较为适宜的采收期。Objective： To explore the effect of different harvest seasons on main bioactive constituents in PolygoniMultifloriRadix （PMR）, and provide scientific evidence for the suitable harvest season for PMR. Methods： HPLC was used to determine the contents of stilbene glycosides, free and conjugated anthraquinones of samples of different harvest seasons from Shibing county of Guizhou province. Component analysis（PCA） was used through the software of SPSS 20. 0 to assess the effect of different harvest seasons on main bioactive constituents. Results： The contents of stilbene glycosides in the samples of different harvest seasons were as follows in descending order： September 〉 October 〉 August 〉 November 〉 December 〉 January. The contents of conjugated anthraquinonesreached the peak onSeptemberand then descended over time. The results of PCA also showed that the comprehensive scores of samples of September and October were higher. Conclusion： Appropriate collecting-times of PMR were in September and October.

关 键 词：何首乌 不同采收期 二苯乙烯苷 蒽醌 

分 类 号：R282.4[医药卫生—中药学]