近红外多光谱荧光分子成像系统的软件设计与实现  

Design and realization of near-infrared multi-spectral fluorescence molecular imaging system software

作　　者：祝永强[1] 乔惠婷[1] 贺进[1] 李德玉[1] 汪待发[1] 

机构地区：[1]北京航空航天大学生物与医学工程学院,北京100191

出　　处：《中国科技论文》2015年第20期2427-2432,共6页China Sciencepaper

基　　金：国家自然科学基金资助项目(61108084);高等学校博士学科点专项科研基金资助项目(20111102120039)

摘　　要：针对自主研制的近红外多光谱荧光分子影像系统,采用模块化和分层设计方式设计了控制和分析软件,有效地实现了硬件模块访问和协调控制、反射和透射成像多光谱成像模式、自动化的数据采集、图像调整和滤波后处理、自发荧光扣除等功能,为用户提供了一体化的控制和分析平台。基于所设计的软件,采用反射和透射成像两种模式进行了小鼠活体荧光分子影像实验,有效地抑制了小鼠本体自发荧光对目标荧光信号的干扰,为荧光分子成像的研究提供了一种有效的工具。The control and analysis software system is designed for our self-produced near-infrared multi-spectral fluorescence molecular imaging system.It provides a stand-alone control and analysis platform for fluorescence molecular imaging,which has the capacity of accessing and coordinately controlling the hardware modules,performing reflection and transmission multi-spectral imaging,automatic data acquisition,image adjustment and filter,and auto-fluorescence reduction.In vivo mouse experiments,this software system is performed in both reflection and transmission imaging modes,where interference from the mouse auto-fluorescence was effectively reduced,and it facilitates the study of fluorescence molecular imaging.

关 键 词：荧光成像 分子成像 自发荧光扣除 数据采集 软件设计 

分 类 号：TP311.52[自动化与计算机技术—计算机软件与理论]