急性脑出血合并2型糖尿病患者动脉功能损伤的抑制作用  

Inhibition of Kabopin for Arterial Injury in Patients with Acute Cerebral Hemorrhage combined with Type 2 Diabetes Mellitus

作　　者：付凯[1] 赵努恩吉雅 

机构地区：[1]内蒙古民族大学附属医院神经内科,内蒙古通辽028000

出　　处：《中外医疗》2015年第14期55-57,共3页China & Foreign Medical Treatment

摘　　要：目的探讨对于急性脑出血合并2型糖尿病患者给予对动脉功能损伤的抑制效果分析。方法将该研究所有患者平均分为对照组和观察组,两组均根据患者具体病情给予手术以及保守治疗急性脑出血,并给予注射胰岛素来稳定血糖,而观察组在此基础上给予卡博平口服。观察两组的临床效果。结果观察组GOS评分良好患者占总病例的56.45%,优于对照组29.03%,对照两组的颈动脉C I M T(内-中膜厚度)、颈A S斑块面积、T C(血清总胆固醇)、T G(甘油三酯)、L D L-C(低密脂蛋白胆固醇)、H D L-C(高密脂蛋白胆固醇)等指标,其中观察组的C I M T、A S斑块面积明显少于对照组(P<0.01),观察组T C、T G和L D L-C水平降低显著(P<0.01),观察组HDL-C则显著升高(P<0.01)。两组空腹血糖均控制较好,而对照组治疗后的餐后血糖明显高于观察组(P<0.05)。结论经临床结果可见,卡博平可有效的控制餐后血糖,从而降低了动脉功能的损伤。Objective To investigate the inhibition of kabopin for arterial injury in patients with acute cerebral hemorrhage com-bined with Type 2 diabetes mellitus. Methods This study all patients were divided into the control group and the observation group, two groups were based on patient specific conditions for the surgery and conservative treatment of acute cerebral hemor-rhage, and to give insulin injections to stabilize blood sugar, while the observation group was treated on the basis of Kabopin oral. To observe the clinical effects of two groups. Results The observation group the GOS score in patients with good cases accounted for 56.45%, better than the control group 29.03%, control group two carotid artery CIMT（IMT）, carotid AS patch area, TC （serum total cholesterol）, TG （triglyceride）, L D L- C （low density lipoprotein cholesterol）, HDL-C （high density lipoprotein cholesterol） and other indicators, including the observation group CIMT, AS plaque area is significantly less than the control group （P〈0.01）, the observation group TC, TG and LDL-C level decreased significantly （P〈0.01）, the observation group HDL-C increased significantly （P〈0.01）. Two groups of fasting blood glucose levels were well controlled, while the control group after treatment of postprandial blood glucose was significantly higher than that in observation group （P〈0.05）. Conclusion The clinical results shows that through effectively controlling of blood glucose after meal Kabopin can reduce the damage of artery function.

关 键 词：卡博平 急性脑出血 2型糖尿病 动脉硬化 

分 类 号：R587.1[医药卫生—内分泌]