倍他司汀联合盐酸氟桂利嗪治疗耳鸣的疗效研究  

Analysis of Clinical Effect of Betahistine Combined with Flunarizine Hy-drochloride in Treatment of Tinnitus

作　　者：魏金龙[1] 赵志明[1] 杨艳[1] 王苏亮[1] 

机构地区：[1]齐齐哈尔医学院附属第二医院,黑龙江齐齐哈尔161006

出　　处：《中外医疗》2015年第14期108-109,共2页China & Foreign Medical Treatment

摘　　要：目的对倍他司汀联合盐酸氟桂利嗪治疗耳鸣的疗效进行分析探讨。方法选取该院于2010年9月—2014年9月收治的102例耳鸣患者,将其随机分为对照组50例和观察组52例,其中对照组给予盐酸氟桂利嗪治疗,观察组患者给予倍他司汀联合盐酸氟桂利嗪治疗。治疗后评估两组的临床疗效、听力指标比较和不良反应。结果治疗后,观察组总有效率为96.2%,明显高于对照组总有效率的54.0%,两组差异有统计学意义(P<0.05);治疗后,观察组的耳鸣程度、听力改善情况均明显优于对照组(P<0.05);对照组和观察组均无严重性的不良反应出现,差异无统计学意义(P>0.05)。结论倍他司汀联合盐酸氟桂利嗪治疗耳鸣的疗效显著,并且无严重不良反应伴发,值得临床推广使用。Objective To investigate the application of betahistine combined with flunarizine hydrochloride in treating tinnitus. Methods Selecting 102 in-patients with tinnitus treated in our hospital from September, 2010 to September, 2014. Randomly di-viding into control group with 50 treated by flunarizine hydrochloride and observation group with 52 treated by betahistine com-bined with flunarizine hydrochloride. The therapeutic effectiveness of the two groups was compared. Results The total efficiency of the observation group is 96.2%, which is higher than 54.0%of the control group（P〈0.05）;The degree of tinnitus, hearing improve-ment in observation group were obviously superior to the control group （P〈0.05）;no obvious differences of adverse reaction were observed between the two groups （P〉0.05）. Conclusion With advantages of good clinical effect and safety inthe treatment of tinni-tus,betahistine combined with flunarizine hydrochloride is worthy of clinic application.

关 键 词：倍他司汀 联合 盐酸氟桂利嗪 治疗 耳鸣 

分 类 号：R764[医药卫生—耳鼻咽喉科]