非瓣膜性房颤抗凝治疗中华法林的应用研究  

Study on Application of Warfarin in Treatment of Non Valvular Atrial Fibrillation Anticoagulation

作　　者：陈隽[1] 洪华山[2] 周一薇[1] 

机构地区：[1]福建中医药大学附属第二人民医院心血管内科,福州350000 [2]福建医科大学附属协和医院干部病房,福州350000

出　　处：《中国继续医学教育》2015年第30期117-119,共3页China Continuing Medical Education

摘　　要：目的：分析非瓣膜性房颤抗凝治疗中华法林的应用效果。方法选择2012年4月～2014年3月80例非瓣膜性房颤患者，根据随机原则分组。其中对照组患者采用阿司匹林抗血小板聚集，实验组患者采用华法林抗凝。随访1年以上，对比两组患者血栓栓塞并发症和出血不良反应的差异。结果经数据统计发现，实验组患者随访期间栓塞并发症发生率低于对照组，组间有统计学差异（P＜0.05）。两组出血不良反应发生率无统计学差异（P＞0.05）。结论在非瓣膜性房颤的抗凝治疗中应用华法林可有效预防血栓形成，同时不增加出血风险。Objective To analyze the effect of therapy of warfarin on non valvular atrial fibrillation anticoagulation.Methods From April 2012 to March 2014, 80 patients with non valvular atrial ifbrillation were grouped according to the random principle. The control group was treated with aspirin anticoagulation, the experimental group were treated with warfarin. Over one year of follow-up, the differences in cerebral embolism complications and bleeding of the two groups were compared.Results The＆amp;nbsp;incidence of cerebral embolism in the experimental group was signiifcantly lower than that in the control group （P＆lt;0.05）. The incidence of adverse reactions in the two groups was not statistically significant （P＆gt;0.05）. Conclusion The application of the Chinese method in the treatment of non valvular atrial ifbrillation can effectively prevent thrombosis, and not increase the risk of bleeding.

关 键 词：非瓣膜性心房颤动 抗凝治疗 华法林 阿司匹林 

分 类 号：R541.75[医药卫生—心血管疾病]