妊娠期糖尿病孕妇产后的糖代谢变化  

Changes of postpartum glucose metabolism in pregnant women with gestational diabetes mellitus

作　　者：丁坚[1] 李小燕[1] 郑琳[1] 刘楼[1] 

机构地区：[1]南京医科大学附属无锡妇幼保健院产科,江苏省214002

出　　处：《江苏医药》2015年第22期2697-2699,共3页Jiangsu Medical Journal

摘　　要：目的探讨妊娠期糖尿病(GDM)孕妇产后糖代谢变化。方法分别于产后42d和2年随访165例GDM孕妇(GDM组)和169例正常孕妇(对照组)的糖代谢相关指标。结果 GDM组产后42d和2年的空腹血糖、口服糖耐量试验2h血糖、空腹胰岛素、胰岛素抵抗指数及糖代谢异常率高于对照组(P<0.05或P<0.01),产后2年GDM组的腰臀比和舒张压高于对照组(P<0.01)。多因素分析提示,孕期使用胰岛素是导致GDM产后糖代谢异常的危险因素,而母乳喂养则是其保护因素。结论 GDM孕妇产后发生糖代谢异常的风险高于正常孕妇,应大力提倡母乳喂养并加强产后随访。Objective To investigate the changes of postpartum glucose metabolism in pregnant women with gestational diabetes mellitus（GDM）.Methods The changes of postpartum glucose metabolism were followed up in 165 GDM puerperants（group A）and 69 normal puerperants without GDM in 6 weeks and 2 years after delivery（group C）.Results Fasting blood glucose,glucose level of 2-hour oral glucose tolerance test,fasting insulin,insulin resistance index and abnormal glucose metabolism rate were all higher in group A than those in group C in 6 weeks and 2 years after delivery（P〈0.05 or P〈0.01）.So did the ratio of waist to hip and diastolic blood pressure（P〈0.01）.Logistic regression analysis revealed that insulin treatment during pregnancy was the risk factor for abnormal postpartum glucose metabolism,while breastfeeding was the protective factor.Conclusion GDM puerperants have an increased risk for abnormal postpartum glucose metabolism.Breastfeeding as well as postpartum follow-up should be strongly advocated in pregnant women with GDM.

关 键 词：妊娠期糖尿病 糖代谢 

分 类 号：R714[医药卫生—妇产科学]