不同麻醉药物对肾移植手术的效果分析  

Effectiveness Analysis of Different Anesthesia Drugs on Renal Transplantation

作　　者：王春生[1] 王文赋[1] 谢铁强[1] 

机构地区：[1]北京军区北戴河疗养院,河北秦皇岛066100

出　　处：《中外医疗》2015年第13期116-118,共3页China & Foreign Medical Treatment

摘　　要：目的探讨不同组合的麻醉药物的对肾移植手术的安全性和临床效果。方法受试者均为肾移植手术患者,随机分为两组,共80例,每组40例。Ⅰ组采用丙泊酚复合瑞芬太尼麻醉,Ⅱ组采用丙泊酚复合舒芬太尼进行麻醉。分别比较两组患者麻醉前后、术中术后的平均动脉压(MAP)、心率(HR)和末梢血氧饱和度(SPO_2),以及患者清醒时间(T)等参数,并严密观察患者不良反应的发生情况。结果麻醉后较麻醉前,两组患者的MAP、HR、SPO_2均降低,Ⅰ组SPO_2明显低于Ⅱ组(P<0.05),MAP和HR两组差异无统计学意义;手术中和手术后,两组受试者的MAP、HR和SPO_2均不存在显著差异;两组患者的清醒时间无显著差异;两组患者一般体动、严重体动、低血压、心动过缓发生率差异无统计学意义;Ⅰ组低氧血症发生率高于Ⅱ组。结论瑞芬太尼和舒芬太尼复合丙泊酚用于肾移植手术的麻醉镇痛效果均比较显著,安全性高,但舒芬太尼在术中生命体征更加平稳,术后恢复较快,效果更佳。Objective To investigate the safety and clinical effect of different anesthesia drugs used in the renal transplantation. Methods We separated the renal transplantation patients into two groups randomly, 20 patients for each group. Group Ⅰ were used remifentanil/ propofol to induce anesthesia, group II were used sufentanil/ propofol to induce anesthesia. MAP, HR, SPO2 and recovery of anesthesia were determined in all patients, and adverse reactions were performed with closely observing. Results MAP, HR and SPO2 decreased after anesthesia in both groups, SPO2 of group Ⅰ was significantly below group II （P〈0.05）, and there was no obvious difference in MAP and HR between the two groups. In and after the surgery, MAP, HR and SPO2 had no sig-nificant difference. The awaking time of both groups had no significant difference. No significant difference was found in body movement, serious body movement, hypotension and bradycardia among the two groups. The occurrence rate of hypoxemia in groupⅠwas significantly above groupII. Conclusion The analgesic effect of remifentanil/propofol and sufentanil/propofol used in the renal transplantation are all markedly and high- security, but group II had more stable vital signs in the surgery and more rapid recovery, so groupIIhad a better efficacy.

关 键 词：丙泊酚 瑞芬太尼 舒芬太尼 肾移植 麻醉 

分 类 号：R64[医药卫生—外科学]