重组牛碱性成纤维细胞生长因子外用凝胶促进包皮环切术后切口愈合的疗效观察  

Clinical observation of recombinant bovine basic fibroblast growth factor gel promote wound healing after circumcision

作　　者：陶佳意[1] 却晖 王丽[1] 张劲松[1] 柳琦[1] 刘辉勇[1] 

机构地区：[1]黄冈市中心医院泌尿外科,湖北黄冈438000

出　　处：《中国美容医学》2015年第21期14-16,共3页Chinese Journal of Aesthetic Medicine

基　　金：黄冈市科技局指导性项目(黄科字【2013】51号)

摘　　要：目的:探讨重组牛碱性成纤维细胞生长因子外用凝胶对于包皮环切术后切口愈合的影响。方法:将342例拟行包皮环切术的患者随机分成两组。观察组172例,手术完成后给予重组牛碱性成纤维细胞生长因子外用凝胶均匀涂抹切口,以后每日换药时涂抹;对照组170例,不给予重组牛碱性成纤维细胞生长因子外用凝胶。观察术后两组切口平均愈合时间、切口平整率。结果:2组患者切口愈合时间和切口平整率有显著性差异(P<0.05),观察组疗效优于对照组。结论:重组牛碱性成纤维细胞生长因子外用凝胶可以加快包皮手术切口的愈合,抑制瘢痕增生,值得临床推广。Objective To investigate the affects of recombinant bovine basic fibroblast growth factor gel were used for wound healing after circumcision. Methods 342 patients who would be circumcised were randomly divided into two groups.The observation group（172 cases）patients were given the recombinant bovine basic fibroblast growth factor gel evenly spread wound when the opention were completed,and also applied daily dressing.The control group（170 cases）were not used recombinant bovine basic fibroblast growth factor gel.The average healing time and flat rate of wound were observed. Results Two groups of average healing time and flat rate of wound were significant difference（P〈0.05）,the observation group was better than the control group. Conclusion The recombinant bovine basic fibroblast growth factor gel can accelerate wound healing circumcision, inhibit scar formation.It is worth for promoting.

关 键 词：重组牛碱性成纤维细胞生长因子 包皮环切术 瘢痕 外用 切口愈合 

分 类 号：R699.8[医药卫生—泌尿科学]