胰岛细胞移植监测的分子影像学进展  

Research progress of molecular imaging in monitoring islet transplantation

作　　者：周金鑫[1] 张一帆[1] 

机构地区：[1]上海交通大学附属瑞金医院核医学科,200025

出　　处：《国际放射医学核医学杂志》2015年第6期478-482,共5页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：基金项目：国家自然科学基金（81171367,81471688）

摘　　要：糖尿病已成为危害人类健康的常见病和多发病。胰岛细胞移植为糖尿病治疗带来新的希望。近年来，分子影像学技术包括光学显像、核素显像、MRI及超声成像等，可在活体条件下无创地进行移植的胰岛细胞显像，为胰岛细胞移植监测提供了灵敏及特异的监测方法。特别是近年来胰高血糖素样肽1类似物胰岛细胞显像的成功，为胰岛细胞移植监测提供了崭新的方法，显示了良好的应用前景。Diabetes is significant public health problem. Islet transplantation has been a promising treatment for diabetes. Recently, molecular imaging methods like optical imaging, radionuclide imaging, MRI and US, could monitor islet transplantation in vivo via non-invasive way and provide high sensitive and specific monitoring methods for islet transplantation. Especially in recent years, the success of islet cell imaging with the glucagon like peptide 1 analogue, brings a new method for the monitoring of islet cell transplantation and demonstrates favorable prospect in clinical practice.

关 键 词：胰岛移植 正电子发射断层显像术 磁共振成像 超声检查 生物发光成像 

分 类 号：R587.1[医药卫生—内分泌]