长序三宝木中的降二萜成分研究（英文）  

Degraded Diterpenoids from Trigonostemon howii

作　　者：唐贵华[1,2] 苑春茂[1] 张于[1] 李顺林[1] 邸迎彤[1] 郝小江[1] 

机构地区：[1]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明650201 [2]中山大学药学院,广州510006

出　　处：《天然产物研究与开发》2015年第11期1843-1846,共4页Natural Product Research and Development

基　　金：supported by the National Natural Science Foundation of China(21432010);The Science Foundation of Yunnan(2014A050);The Technological leading talent project of Yunnan;the Xibuzhiguang Project(grant to Y.T.D.)

摘　　要：从长序三宝木(Trigonostemon howii)茎的化学成分研究中发现4个降二萜化合物,其中新化合物trigohowilone A(1)经波谱数据包括核磁、质谱、比旋光等鉴定为trigoxyphin P的对映异构体。已知化合物结构确定为trigoxyphin Q(2),trigohowilol H(修订后的俗名)(3)和9-O-demethyltrigonostemone(4)。所有化合物均为首次从该植物中分离得到。Phytochemical investigation on the stems of Trigonostemon howii resulted in the isolation of four degraded diterpenoids. A new compound, trigohowilone A （1）, was defined as the enantiomer of trigoxyphin P based on the analy- ses of its spectroscopic data including NMR,MS,and the specific rotation data. The structures of known compounds were identified as trigoxyphin Q （2） ,trigohowilol H （revised trivial name） （3） ,and 9-O-demethyltrigonostemone （4）. All compounds were obtained from the plant for the first time.

关 键 词：大戟科 长序三宝木 降二萜 trigohowilone A (-)-trigoxyphin P 

分 类 号：R284.1[医药卫生—中药学] Q946.91[医药卫生—中医学]