肺炎支原体肺炎患儿血清C-反应蛋白及免疫球蛋白水平的变化  

Changes of serum C-reactive protein and immunoglobulin levels in children with Mycoplasma pneumoniae pneumonia

作　　者：高劲[1] 邰海服[1] 张晓娟[1] 李志厂 徐国成[1] 

机构地区：[1]皖南医学院第一附属医院弋矶山医院儿科,安徽芜湖241001

出　　处：《皖南医学院学报》2015年第6期556-558,共3页Journal of Wannan Medical College

摘　　要：目的：了解并分析肺炎支原体肺炎（Mycoplasma pneumoniae pneumonia,MPP）患儿CRP及免疫球蛋白的变化。方法：病例组（MPP组）为2014年12月~2015年5月于本院住院治疗的MPP患儿60例,对照组为同期门诊体检的健康儿童60例,回顾分析两组儿童外周静脉血中CRP及免疫球蛋白的水平,并作统计学分析。结果：与对照组相比,MPP组的Ig A表达水平显著降低,而CRP、Ig E、Ig M及Ig G水平显著升高,差异有统计学意义（P〈0.05）。结论：CRP和免疫球蛋白可能有助于MPP的早期诊断和病情评估;体液免疫在MPP发病过程中起着重要作用。Objective： To understand and analyze the changes of serum C-reactive protein（ CRP） and immunoglobulin levels in children with Mycoplasma pneumoinae pneumonia（ MPP）. Methods： CRP and immunoglobulin level changes were maintained and statistically analyzed in 60 MPP cases treated in our hospital from December 2014 through May 2015,and another 60 healthy children undergone physical examination on outpatient basis at the corresponding periods were recruited as concurrent controls. Results： Compared with control group,Ig A level was significantly decreased,whereas levels of CRP,Ig E,Ig M and Ig G were markedly elevated in MPP group（ P〈0. 05）. Conclusion： Determination of CRP and immunoglobulin levels may contribute to establishing early diagnosis and severity of the condition in children with MPP,and humoral immune dysfunction plays an important role in the pathogenesis of MPP.

关 键 词：儿童 肺炎支原体肺炎 CRP 免疫球蛋白 

分 类 号：R725.6[医药卫生—儿科]