机构地区:[1]保定市第一中心医院康复医学科,河北保定071000 [2]保定市第一中心医院医务科,河北保定071000
出 处:《中国针灸》2015年第12期1243-1246,共4页Chinese Acupuncture & Moxibustion
摘 要:目的:比较穴位注射配合火针与口服维生素C、维生素B2及皮下注射转移因子治疗心脾积热型复发性口腔溃疡的临床疗效差异。方法:将158例心脾积热型复发性口腔溃疡患者随机分为观察组和对照组,每组79例。观察组选取心俞、脾俞、足三里,穴位注射双黄连注射液各1mL,每周3次,共治疗2周;火针点刺溃疡面及周围黏膜,每日1次,共治疗3次。对照组口服维生素C片100mg、维生素B2片20mg,每日3次;皮下注射转移因子,每次2mL(3mg),每周2次,共治疗2周。观察两组患者治疗前后症状体征积分、疼痛视觉模拟量表(VAS)评分的变化,以及治疗后溃疡愈合时间、溃疡复发情况,并比较两组临床疗效。结果:观察组总有效率为92.4%(73/79),优于对照组的77.2%(61/79,P<0.01)。观察组与对照组治疗前后症状体征积分、VAS疼痛评分比较,差异均有统计学意义(P<0.01);治疗后观察组症状体征积分、VAS疼痛评分减少比对照组明显,差异有统计学意义(P<0.01)。观察组溃疡愈合时间早于对照组[(3.87±1.01)天vs(6.22±0.53)天,P<0.01]。观察组复发率低于对照组[22.7%(17/75)vs 50.0%(36/72),P<0.01]。结论:穴位注射配合火针治疗复发性口腔溃疡疗效优于口服维生素及皮下注射转移因子,止痛效果好、见效快,可改善相关症状,缩短溃疡愈合时间,且疗效巩固。Objective To compare the clinical efficacy between the combined acupuncture therapy of acupoint injection and fire needling and the orat administration of vitamin C and Bz as well as subcutaneous injection of transfer factor. Methods One hundred and fifty-eight patients of recurrent oral ulcer (ROU) differentiated as heat accumulation in the heart and spleen were randomized into an observation group and a control group, 79 cases in each one. In the observation group, Xinshu (BL 15), Pishu (BL 20) and Zusanli (ST 36) were selected for acupoint injection of shuang huanglian injection, 1 mL at each point, three times a week, for 2 weeks totally. Additionally, fire needling was applied to the ulcer lesion and peripheral mucosa, once a day, totally for 3 times. In the control group, vitamin C 100 mg and vitamin B2 20 mg were prescribed for oral administration, three times a day; and subcutaneous injection of transfer factor was applied, 2 mL (3 mg), twice a week, for 2 weeks totally. The score of symptoms and physical signs and the visual analogue scale (VAS) were observed before and after treatment, as well as the time of ulcer healing and ulcer recurrence in the patients of the two groups. The clinical efficacy was compared between the two groups. Results The total effective rate was 92.4% (73/79) in the observation group, better than 77. 2% (61/79) in the control group (P〈0. 01). The differences in the score of symptoms and physical signs and VAS score before and after treatment were significant statistically in the observation group and the control group (all P〈0.01). The score of symptoms and physical signs and VAS score after treatment in the observation group were reduced significantly as compared with those in the control group (both P〈0.01). The time of ulcer healing in the observation group was earlier than that in the control group [ (3.87± 1.01 )d vs (6.22 ± 0.53)d, P〈0.01]. The recurrence rate in the observation was lower than that in the contr
分 类 号:R246.8[医药卫生—针灸推拿学]
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