太田痣患者352例生活质量评估及影响因素分析  

The Analysis of Quality of Life and Influence Factors in 352 Patients with Nevus of Ota

作　　者：王娟[1] 王中影[2] 姚秀华[1] 张兰芳[1] 张思平[1] 胡白[1] 

机构地区：[1]安徽医科大学附属安徽省立医院皮肤科,安徽合肥230001 [2]安徽医科大学第一附属医院皮肤科,安徽合肥230022

出　　处：《中国皮肤性病学杂志》2015年第12期1284-1287,共4页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨太田痣(nevus of Ota)对患者生活质量的影响及其影响因素。方法使用皮肤病生活质量指数调查表(dermatology life quality index,DLQI)调查352例太田痣患者的生活质量,单因素、多因素分析影响生活质量的因素。结果太田痣患者生活质量轻度、中度受影响者分别占45.17%和47.16%,其余7.67%患者对生活质量重度影响;单因素分析显示性别、发病年龄、皮损呈单/双侧分布、居住地、受教育程度、工作学习状态、皮损部位、皮损面积以及黏膜是否受累有统计学意义(P<0.05);多元回归分析显示性别、皮损面积、发病年龄是影响太田痣患者生活质量的主要因素(P<0.05,OR>1)。结论太田痣对绝大多数患者生活质量有着轻、中度影响,女性、皮损面积大、发病较晚是影响太田痣患者生活质量的主要因素。Objective To assess the quality of life （QoL） in patients with nevus of Ota, and to discuss the influence factors of QoL. Methods Dermatology Life Quality Index（DLQI） was used to analyze QoL and its influence factors in 352 patients with nevus of Ota, using both single factor and muhifactor analysis. Results The number of patients with mild and moderate impairment of QoL were 159 （45. 17% ） and 166（47. 16% ） , respectively. QoL was severely impaired in 27 cases（7.67% ）. Single factor analysis showed that the influence factors of QoL included gender, age of onset, unilateral/ bilateral distribution of lesions, residential address, education level, employment status,lesions site and size, and mucosal involvement （ P 〈 0. 05 ）. Multiple regression analysis showed that gender, lesion size and age of onset were the major impact factors （ P 〈 0. 05, OR 〉 1 ）. Conclusion Most patients with nevus of Ota had mild to moderate impairments of QoL. Female,larger lesion size,and late onset were the major factors affecting QoL in patients.

关 键 词：太田痣 皮肤病生活质量指数 生活质量 影响因素 

分 类 号：R758.51[医药卫生—皮肤病学与性病学]