门冬氨酸阿奇霉素静滴辅助痰热清雾化吸入治疗小儿支原体肺炎疗效分析  

Azithromycin Aspartate Intravenous Auxiliary Tanreqing Atomization In-halation Treatment of Children with Mycoplasma Pneumonia

作　　者：何青 

机构地区：[1]濮阳县妇幼保健院儿科,河南濮阳457199

出　　处：《中外医疗》2015年第21期118-119,共2页China & Foreign Medical Treatment

摘　　要：目的探讨门冬氨酸阿奇霉素静滴辅助痰热清雾化吸入治疗小儿支原体肺炎的临床效果。方法将治疗对象150例,随机分为观察组与对照组各75例,两组均给予常规处理,观察组在常规处理的基础上,给予门冬氨酸阿奇霉素治疗,对照组则给予红霉素服用,并将同等剂量红霉素加入5%葡萄糖200 m L内静脉点滴。两组均7 d为1疗程,连续治疗2个疗程后评定整体疗效,数据进行统计学处理(χ2检验)。结果两组患者痊愈、有效、无效、总有效率比较(χ2=9.101、7.245、10.010、8.979,均P<0.01),观察组整体疗效明显优于对照组,具有非常显著性差异;两组患者的纳差、腹部疼痛不适、皮疹、呕吐之不良反应发生情况比较(χ2=7.102、5.324、4.076、5.558,均P<0.05)观察组不良反应发生率显著低于对照组,差异有统计学意义。结论门冬氨酸阿奇霉素静滴辅助痰热清雾化吸入对小儿支原体肺炎治疗效果尚佳,不良反应发生少。Objective To observe the clinical effect of Azithromycin aspartate intravenous auxiliary Tanreqing atomization inhalation treatment of children with mycoplasma pneumonia. Methods Treatment object 150 cases, were randomly divided into observation group and control group, with each 75 cases, and two groups were given conventional treatment. Observation group, on the basis of conventional treatment, was given Azithromycin aspartate treatment, while control group was treated with erythromycin and equal doses of erythromycin was added to 200 mL of 5% glucose intravenously. Both groups take 7 d as 1 course of treatment, and after continuous treatment of 2 courses, the evaluation of the overall efficacy were made, and data were statistically processed（Х^2test）. Results Comparison between two groups of patients on recovery, effective, ineffective, total effective rate（Х^2=9.101, 7.245,10.010, 8.979, all P〈0.01）, the overall effect of the observation group was significantly better than the control group, with significant difference; comparison between two groups of patients on occurrence of adverse reactions with anorexia, abdominal pain, rash,nausea and vomiting,（Х^2=7.102, 5.324, 4.076, 5.558, all P〈0.05）, the adverse reaction incidence rate of observed group was significantly lower than that of the control group, the difference is statistically significant. Conclusion Treatment effect of Azithromycin aspartate intravenous auxiliary Tanreqing atomization inhalation treatment of children with mycoplasma pneumonia, was still good,and adverse reactions occurred less.

关 键 词：小儿支原体肺炎 门冬氨酸阿奇霉素静滴 痰热清雾化吸入 

分 类 号：R725.6[医药卫生—儿科]