2012~2014年我院药品不良反应报告分析  

Analysis of adverse drug reaction case reports from 2012 to 2014 in a hospital

作　　者：蔡杰[1] 李琼[1] 黎汉坤[1] 苏美霞[1] 郑亮[1] 

机构地区：[1]湛江中心人民医院,湛江524037

出　　处：《北方药学》2015年第12期145-146,共2页Journal of North Pharmacy

摘　　要：目的：了解我院药品不良反应（ADR）发生的特点,为临床合理用药提供参考。方法：收集我院2012年1月~2014年12月上报的391例ADR报告进行分类统计、分析。结果：391例ADR报告中,60岁以上老年患者所占比例较大,涉及药品21个大类,其中抗微生物药物致ADR例数最多,最常见的临床表现为皮肤及其附件损害,给药途径以静脉滴注居多。结论：医护人员应加强不良反应监测工作,特别是对老年病患者、非经胃肠道给药、抗微生物药物及中药注射剂应引起重视,提高药物临床合理应用水平,减少ADR。Objective： In order to provide reference for clinical administration, we clarify the situation of adverse drug reaction（ADR）in our hospital. Methods： A total of 391 ADR case reports in our hospital collected from January 2012 to December 2014 were classified and analyzed statistically. Results：In 391 ADR case reports, senile patients over 60 formed a large proportion of it, it also involves 21 kinds of drugs, ADR causing by antimicrobial agent had higher incidence. Damage of skin and its accessories was the most common clinical presentation , the major ADRs were induced by injection. Conclusions： We should strengthen the monitoring of ADR, and pay more attention to it , especially senile patients, parenteral administration, antimicrobial agent, traditional Chinese medicine injection, and intravenous injection. Simultaneously, promote the level of rational drug use in clinical treatment , reduce the incidence of adverse reactions.

关 键 词：药品不良反应 合理用药 非经胃肠道给药 

分 类 号：R969.3[医药卫生—药理学]