影响腹膜透析患者多发性腹膜炎相关因素的Logistic回归分析  

The Logistic regression analysis of the risk factors affecting the multiple peritonitis in patients with peritoneal dialysis

作　　者：冯明亮[1] 张辉[2] 

机构地区：[1]广东省江门市中心医院肾内科,广东江门529000 [2]广东省江门市中心医院重症医学科,广东江门529000

出　　处：《中国医药导报》2015年第35期103-106,共4页China Medical Herald

基　　金：广东省江门市第一批科技计划项目(江科[2013]81号-22)

摘　　要：目的探讨影响腹膜透析患者多发性腹膜炎的相关因素。方法以2013年2月～2015年7月在江门市中心医院肾内科发生腹膜透析相关性腹膜炎的91例患者为研究对象，46例多发性腹膜炎患者为观察组，45例单次发生腹膜炎患者为对照组；以Logistw回归分析法分析影响其多次发生腹膜炎的相关因素。结果观察组患者拔管率为15．2％，显著高于对照组的2．2％（P〈0．01）。两组患者在性别、年龄、透析操作者、文化程度和原发病等方面比较差异无统计学意义（均P〉0．05）。观察组在抗感染疗程不足（41．3％）和未及时治疗方面（67．4％）显著高于对照组（17．8％、30．4％）（P〈0．05、P〈0．01）。观察组透析龄〈1年者占37．0％，明显低于对照组的73-3％（P〈0．01）。观察组低血红蛋白和低血浆白蛋白、高c反应蛋白比例明显高于对照组（P〈0．05）。在多因素分析中，长透析龄（OR=1．026，95％CI：1．001～1．125，P=0．005）、低血红蛋白（OR=2．507，95％CI：1．811～4．708，P=0．000）、低血浆白蛋白（OR=2．900，95％CI：1．443～3．558，P=0．000）、未及时治疗（OR=2．347，95％CI：1．584～4．617，P=0．000）、抗感染疗程不足（OR=2．358，95％CI：1．393～3．621，P=0．000）为频繁发生腹膜炎的影响因素。结论未及时治疗、抗感染疗程不足、长透析龄、血红蛋白和血浆白蛋白偏低预示腹膜透析患者可能会多次发生腹膜炎。Objective To analyze the risk factors affecting the multiple peritonitis in patients with peritoneal dialysis. Methods Ninety one cases of patients who occurred peritonitis related to peritoneal dialysis in Department of Nephrology of Jiangmen Central Hospital from February 2013 to July 2015 were selected as the research objects, among whom, 46 patients with multiple peritonitis were taken as the observation group, and 45 patients with single peritonitis were taken as the control group. Logistic regression analysis was used to analyze the related factors affecting the multiple peritonitis. Results The extubation rate in the observation group was 15.2%, which was significantly higher than that in the control group （2.2%） （P 〈 0.01）. There were no significant differences in genders, ages, dialysis operators, culture levels and the primary diseases between the two groups （all P 〉 0.05）. The rates of lack of anti infection treatment （41.3%） and not treated in time （67.4%） in the observation group were significantly higher than those in the control group （17.8%, 30.4%） （P 〈 0.05, P 〈 0.01）. In the observation group, the proportion of patients whose dialysis treatment time was less than 1 year was 37.0%, which was significantly lower than that in the control group （73.3%） （P 〈 0.01）. The percentages of low hemoglobin, low plasma albumin and high C reactive protein in the observation group were higher than those of control group （/9 〈 0.05）. In multivariate analysis, long dialysis ages （OR = 1.026, 95%CI： 1.001-1.125, P = 0.005）, low hemoglobin levels （OR = 2.507, 95%CI： 1.811-4.708, P = 0.000）, low plasma albumin levels （OR = 2.900, 95%CI： 1.443-3.558, P = 0.000）, not treated in time （OR = 2.347, 95%CI： 1.584-4.617, P = 0.000） and lack of anti infection treatment （OR = 2.358, 95%CI： 1.393-3.621, P = 0.000） were the factors affecting the incidence of multiple peritonitis. Conclusion Being delayed treatment, lack of anti infection treatment

关 键 词：腹膜透析 多发性腹膜炎 影响因素 

分 类 号：R656.4[医药卫生—外科学]