RPR与TPPA在梅毒血清测定中的临床价值分析  

Analysis the Clinical Value of RPR and TPPA in Measure Syphilis Serum

作　　者：奚敏芬 

机构地区：[1]苏州工业园区疾病防治中心检验科,215021

出　　处：《中国继续医学教育》2015年第31期42-43,共2页China Continuing Medical Education

摘　　要：目的观察RPR与TPPA在梅毒血清测定中的临床价值。方法选取2014年2月一2014年12月我市疾病防治中心检验科720例接受梅毒血清测定的受检人员作为研究对象，受检人员均行RPR以及TPPA梅毒血清检测。比较两种测定方法阳性检出率、敏感度与特异性。结果本组720例受检者中34例梅毒血清标本经临床检验中心确诊为阳性，阳性率为4．72％；其中TPPA阳性检出例数为30例，阳性率为4．17％，RPR阳性检出例数为23例，阳性诊断率为3．19％，两种方法阳性检出率对比，P〈0．05，差异具有统计学意义。TPPA不同分期阳性检出率高于RPR，P〈0．05，差异具有统计学意义。结论梅毒螺旋体明胶凝集试验用于梅毒血清测定效果满意，其阳性诊断符合率以及不同分期阳性检出率高于快速血浆反应素环状卡片试验。Objective To observe the RPR and TPPA in syphilis clinical value in the determination of serum. Methods Selected 720 patients who underwent syphilis gien from February 2014 to December 2014 in city centers for disease prevention and control of clinical laboratory determination in the serum as the study object, all of them were adopt the RPR and TPPA in syphilis serum test. Compared two methods for determining the positive detection rate, sensitivity and specificity. Results There were 34 cases in 720 cases of syphilis serum specimens confirmed by clinical examination center for positive, positive rate is 4.72%, TPPA positive detection of cases of 30 cases, the positive rate was 4.17%, positive RPR detected cases for 23 cases, positive predictive value was 3.19%, compared the positive rate two methods, P〈0.05, had difference statistically significance. TPPA positive rate in different stages was higher than the RPR, P〈0.05, had difference statistically significance. Conclusion The determination of treponema pallidum gelatin agglutination test for syphilis serum effect is satisfied, the positive rate positive diagnosis coincidence rate, and different stage was higher than the rapid plasma reagin ring card test.

关 键 词：梅毒血清标本 检测 快速血浆反应素环状卡片试验 梅毒螺旋体明胶凝集试验 

分 类 号：R725.6[医药卫生—儿科]