重症感染患者早期应用小剂量肝素治疗的效果初步观察与评估  

Assess and Preliminary Observation Effect of Application Lowdose Heparin Therapy in Treatment of Patients With Severe Infection in Early

作　　者：孙胜利[1] 卢博[1] 许艳军[1] 莫逊[1] 

机构地区：[1]徐州市中心医院,221009

出　　处：《中国继续医学教育》2015年第31期178-179,共2页China Continuing Medical Education

摘　　要：目的 研究重症感染患者早期应用小剂量肝素治疗的临床效果.方法 选取2011年11月～2014年12月我院收治的42例重症感染患者作为研究对象,并随机分为对照组和实验组,各21例.对照组采用常规ICU治疗,实验组在对照组的基础上早期加用小剂量肝素,对比两组重症感染患者的各项血样指标、住院时间和生存率.结果 治疗1 d后,对照组重症感染患者的血小板计数高于实验组,P＜0.05,差异具有统计学意义.治疗7 d后,对照组的PT和APTT均高于实验组, P＜0.05,差异具有统计学意义.与对照组比较,实验组住院时间更短,生存率更高,P＜0.05,差异具有统计学意义.结论 早期应用小剂量肝素治疗重症感染具有显著的临床效果.Objective The clinical effects of low-dose heparin therapy in patients with early severe infection study.Methods Selected 42 cases of severe infections in patients from November 2011 to December 2014 in our hospital as the object study, were randomly divided into the control group and experimental group, each group had 21 cases. The control group with conventional treatment, the experimental group basis of early plus treatment with low-dose heparin, compared two groups of patients with severe infection of the blood indicators of hospital stay and survival.Results After treatment the day, the control group of patients with severe infection platelet count higher than the experimental group,P〈0.05, was difference had statistically significance, seven days after treatment, the control group of patients with PT and APTT were higher in the experimental group, P〈0.05, was difference had statistically significance. compared with the control group of patients, hospital stay of patients in the experimental group was shorter survival rates higher,P〈0.05, was difference had statistically significance.Conclusion Early low-dose heparin in patients with severe infection has good clinical effect.

关 键 词：重症感染 肝素 临床效果 

分 类 号：R9[医药卫生—药学]