小儿急性上呼吸道病毒感染病原学与临床特征研究  

Pathogenic and clinical evaluation on the acute upper respiratory infections among outpatient clinic children

作　　者：朱益飞[1] 张晨美[2] 周招美[1] 

机构地区：[1]江山市人民医院儿科,浙江江山324100 [2]浙江大学附属儿童医院PICU,浙江杭州310003

出　　处：《中华医院感染学杂志》2015年第23期5473-5474,5502,共3页Chinese Journal of Nosocomiology

基　　金：浙江省科技重大专项基金资助项目(2012C13024-3)

摘　　要：目的探讨儿童急性上呼吸道病毒感染病原学调查,并对其临床特征进行分析,为儿童急性上呼吸道感染的治疗提供参考依据。方法选取医院2011年2月-2014年2月门诊收治的急性上呼吸道感染患儿150例进行研究,采用多重聚合酶链反应方法检测,并进行标本病毒的分离,观察病原体的种类及其临床特征,数据采用SPSS 11.0软件进行统计分析。结果共送检标本150份,阳性标本118份,检出率为78.67%;其中最常见为流感病毒,43株占36.44%;患儿病毒检出率0~1岁为73.91%、1~3岁为91.23%、3~6岁为55.93%、6~10岁为27.27%,以1~3岁病毒检出率最高,与其他年龄段相比,差异均有统计学意义（P〈0.05）。结论小儿急性上呼吸道感染病毒种类较多,且不同年龄段、不同季节其变异性较大,临床医师需要根据患儿的疾病临床特征,及早进行病毒的检测,为患儿早期的治疗提供更好的依据。OBJECTIVE To study the pathogenic and clinical treatment on the acute upper respiratory infections a- mong outpatient clinic children so as to provide a better way to treat the acute upper respiratory infections. METHODS Totally 150 children with acute upper respiratory infections in outpatients from Feb. 2011 to Feb. 2014 were investigated. Multiplex polymerase chain reaction was adopted to explore the test. The specimens of the virus were isolated to observe the types and clinical features of those pathogens. SPSS 11.0 was adopted for statis- tical analysis. RESULTS Totally 150 samples were inspected, including 118 positive ones and the detection rate was 78.67%. One of the most common pathogens was influenza virus, with 43 cases accounted for 36.44%, followed by 31 cases of respiratory syncytial virus accounted for 26.27 %. The detection rate of patients aged 0-1, 1-3, 3~6, 6-10 were 73.91M, 91.23%, 55.93% and 27.27%. Compared with other age groups, children aged 1-3 were more susceptible to virus and the differences were significant （P〈0.05）. CONCLUSION Children suffer from va- rious viral infections in upper respiratory tracts and different age groups in different seasons have different detec- tion rates. Clinicians need to detect virus early based on clinical features of the disease in children so that better treatments can be chosen.

关 键 词：上呼吸道 病毒感染 病原学 临床特征 

分 类 号：R562.1[医药卫生—呼吸系统]