体成分与骨密度检测在2型糖尿病患者中的应用研究  

Application of body composition and bone mineral density analysis in patients with type 2 diabetes mellitus

作　　者：张桂兰[1] 黄淑玉[1] 

机构地区：[1]湖北省孝感市中心医院体检中心,孝感432000

出　　处：《江苏预防医学》2015年第6期7-9,共3页Jiangsu Journal of Preventive Medicine

摘　　要：目的 探讨男性2型糖尿病（T2DM）患者体成分与骨密度（BMD）的关系。方法 随机选取男性确诊T2DM患者107例和健康体检人群110例作为研究对象,完善体成分及血脂、血尿酸、糖化血红蛋白等生化检查,同时测定腰椎1-4和左股骨大转子BMD值,并对资料进行分析。结果 两组研究对象的年龄、高TC率、高UA率差异均无统计学意义（P值均〉0.05）;患病组BMI、BMD、高糖化血红蛋白、高TG率、低HDL-C率均高于非患病组（P值均〈0.05）;多重线性回归分析表明,BMD与年龄、糖化血红蛋白值呈显著负相关;T2DM患者不同体重、不同部位的体成分BMD差异均有统计学意义（P〈0.01）。结论 BMI、肌肉含量和脂肪含量对男性T2DM患者BMD有直接影响。加强体育锻炼,增加肌肉含量,减少腹部脂肪含量,可预防骨质疏松。Objective To study correlation between body composition and bone mineral density （BMD） among male type 2 diabetes （T2DM） patients. Methods A total of 107 T2DM patients and 110 healthy men were randomly selected as subjects, whose body composition and biomedical indicators such as blood lipids, blood uric acid and glycosylated hemoglobin were analyzed,BMD of lumbar spines（1 -4）, together with left femur and greater trochanter were determined. All data were subjected to epidemiological analysis. Results No statistical difference were observed for age, high TC rate and high UA rate between the two test groups （all P〉0.05）. BMI, BMD, glycosylated hemoglobin ,TG rate and low HDL-C rate in T2DM patients group were higher than those in control group （all P〈0.05）. Multiple linear regression analysis showed that BMD had statistical negative correlation with age and glycosylated hemoglobin, statistical difference were observed between BMDs for T2DM patients with different weight and body composition（P〈0. 01）. Conclusion BMI, muscle content and fat content had a direct effect on BMD among T2DM patients. Strengthening physical exercise and increasing muscle content, together with reduction of abdominal fat content can prevent osteoporosis.

关 键 词：体成分 骨密度 2型糖尿病 男性 骨质疏松 

分 类 号：R587.1[医药卫生—内分泌]