Animal model of repetitive mild traumatic brain injury for human traumatic axonal injury and chronic traumatic encephalopathy  

作　　者：Leyan Xu 

机构地区：[1]Division of Neuropathology, Department of Pathology, The Johns Hopkins University School of Medicine

出　　处：《Neural Regeneration Research》2015年第11期1731-1732,共2页中国神经再生研究（英文版）

摘　　要：Chronic traumatic encephalopathy（CTE）is a chronic neurodegenerative disease featured with tauopathy.CTE is tightly related with repetitive mild traumatic brain injury（m TBI）,which is interchangeably known as concussion（Mc Kee et al.,2009,2013）.This disease is differentiated by neuropathological features from other neurological diseases that involve tau protein aggregation and tangle formation abnormalities like Alzheimer＇s disease （AD）, frontotemporal dementia, and Parkinson- ism linked to chromosome 17 （FTDP-17）.Chronic traumatic encephalopathy（CTE）is a chronic neurodegenerative disease featured with tauopathy.CTE is tightly related with repetitive mild traumatic brain injury（m TBI）,which is interchangeably known as concussion（Mc Kee et al.,2009,2013）.This disease is differentiated by neuropathological features from other neurological diseases that involve tau protein aggregation and tangle formation abnormalities like Alzheimer＇s disease （AD）, frontotemporal dementia, and Parkinson- ism linked to chromosome 17 （FTDP-17）.

关 键 词：TBI Animal model of repetitive mild traumatic brain injury for human traumatic axonal injury and chronic traumatic encephalopathy 

分 类 号：R651.15[医药卫生—外科学] R-332[医药卫生—临床医学]