血液灌流序贯高容量血液滤过对感染性休克患者降钙素原水平的影响  

Influence of hemoperfusion sequential high volume hemofiltration on procalcitonin level in septic shock patients

作　　者：李盘石[1] 张红梅[1] 邓永进[1] 杜丽华[1] 

机构地区：[1]东莞市人民医院ICU,523000

出　　处：《中国实用医药》2015年第31期11-12,共2页China Practical Medicine

摘　　要：目的探讨血液灌流序贯高容量血液滤过对感染性休克患者降钙素原水平的影响。方法 37例感染性休克患者,随机分为对照组(18例)和治疗组(19例)。对照组给予常规抗感染等综合治疗,治疗组在常规综合治疗基础上,应用血液灌流序贯高容量血液滤过治疗,测定两组患者入住ICU及治疗72 h后血清降钙素原水平。结果两组入住ICU时血清降钙素原比较,差异无统计学意义(P>0.05);治疗72 h后血清降钙素原组间相比差异具有统计学意义(P<0.05)。结论血液灌流序贯高容量血液滤过可以下调感染性休克患者降钙素原的表达,对感染性休克的治疗有益。To investigate influence of hemoperfusion sequential high volume hemofiltration on procalcitonin level in septic shock patients.Methods A total of 37 septic shock patients were randomly divided into control group （18 cases） and treatment group （19 cases）. The control group received comprehensive treatment by conventional anti-infection, and the treatment group received additional hemoperfusion sequential high volume hemofiltration for treatment. Procalcitonin levels in the two groups were detected in ICU admission and 72 h after treatment.Results There was no statistically significant difference of serum procalcitonin between the two groups in ICU admission （P〉0.05）, while the difference after 72 h of treatment had statistical significance between the two groups （P〈0.05）.Conclusion Hemoperfusion sequential high volume hemofiltration can reduce expression of procalcitonin in septic shock patients, and it is beneficial for septic shock treatment.

关 键 词：血液灌流 高容量血液滤过 感染性休克 降钙素原 

分 类 号：R459.7[医药卫生—急诊医学]