婴幼儿肺炎支原体肺炎的临床特点  

The characteristics of mycoplasma pneumoniae pneumonia in children with different ages

作　　者：郑承宁[1] 王云峰[1] 李绚[1] 惠秦[1] 高新营[1] 张凯[1] 

机构地区：[1]中日友好医院儿科,北京100029

出　　处：《中日友好医院学报》2015年第6期331-333,351,共4页Journal of China-Japan Friendship Hospital

摘　　要：目的:探讨婴幼儿肺炎支原体肺炎的临床特点。方法:对比研究38例婴幼儿肺炎支原体肺炎与133例儿童肺炎支原体肺炎的临床资料、实验室检查及影像学检查结果。结果:婴幼儿组住院前病程显著长于儿童组(10.26±5.30 vs.7.70±6.42,P<0.05),喘息显著多于儿童组(7.89%vs.3.76%,P<0.05);肺外合并症中,婴幼儿组消化系统症状和心肌损伤多见;儿童组发热多见,伴多种肺外表现。实验室检查,除婴幼儿组的肌酸激酶同功酶(CK-MB)和儿童组的C反应蛋白显著升高外,其余在正常范围或轻度升高。影像学上,婴幼儿组支气管肺炎多见,后者节段性实变较多见。2组大环内酯类治疗均有效,住院天数无显著性差异。结论:婴幼儿肺炎支原体肺炎喘息多见,影像学以支气管肺炎表现较多,而儿童肺炎支原体肺炎发热较多见,多累及节段。Objective：To investigate the clinical characteristics of mycoplasma pneumoniae pneumonia（MPP）in children with different ages.Methods：A total of 171 children with MPP admitted to our hospital from Aug. 2010 to Aug.2013.They were analyzed by dividing into two age groups：the younger group （infant and young children ≤ 3 years, n=38）and older group （age〉3 years,n= 133 ）.Clinical symptoms, main laboratory and imaging results of MPP were compared.Results：Children in younger group had significantly longer duration before ad- mission and higher proportion with wheezing（7.89% vs 3.76% ,P〈0.05 ）.The gastrointestinal symptoms and my- ocardial damage were more prevalent in the younger group,while fever and extra-pulmonary manifestations were more common in the older group.Abnormal reatine kinase isoenzyme-MB （CK-MB）in younger group and C-reactive protein in older group was statistically higher than the counterpart（P〈0.05）.Chest Radiology showed more bronchopneumonia in the younger but more segmental consolidation in the older.Macrolide was effective for both groups.There were no difference in the length of stay in hospital.Conclusion：More infants and young children with MPP present wheezing and bronchopneumonia,in contrast,more patients in the older group pre- sented fever and pulmonary segmental consolidation.

关 键 词：婴幼儿 肺炎支原体肺炎 临床特点 

分 类 号：R725.6[医药卫生—儿科]