广西地区1022例慢性肝衰竭患者中医证候回顾性分析  

A retrospective analysis of TCM syndromes in 1022 patients with chronic liver failure in Guangxi,China

作　　者：毛德文[1] 盛庆寿[2] 唐农[1] 王娜[1] 龙富立[1] 徐刚[1] 陈小明 

机构地区：[1]广西中医药大学第一附属医院,广西南宁530023 [2]广西中医药大学附属瑞康医院,广西南宁530011 [3]广东省佛山市顺德区中医院,广东佛山528333

出　　处：《湖南中医杂志》2015年第11期10-12,共3页Hunan Journal of Traditional Chinese Medicine

基　　金：国家"十二五"传染病重大科技专项(编号:2012ZX10005005-001-002);广西壮族自治区自然科学基金课题(编号:2012GXNSFAA053121;2014GXNSFBA118207;2015GXNSFAA139208);广西壮族自治区高等学校高水平创新团队及卓越学者计划资助项目

摘　　要：目的:回顾性分析广西地区慢性肝衰竭(CLF)患者的病因病机、中医证候规律及预后转归,为本病的中医、中西医结合诊治提供科学依据。方法:采用回顾性调查方法,对广西地区1022例CLF患者的病因、中医证候、预后进行分析。结果:肝硬化是CLF的高危因素;病毒性肝炎、肝硬化、乙醇是CLF的主要病因,尤其是乙肝病毒(HBV);本病辨证定性多以血瘀、气虚、阳虚、湿热、热毒为主;排在前3位的证型分布是瘀热发黄证、气虚瘀黄证、阳虚瘀黄证;阳虚瘀黄证和脾肾阳虚证患者的病死率更高。结论:广西地区CLF患者的主要病因是肝硬化和HBV,气虚、阳虚在CLF中医证候中表现相当突出,这对临床治疗具有重要的现实指导意义。Objective： To retrospectively investigate the etiology, pathogenesis, traditional Chinese medicine （TCM） syndrome patterns, and prognosis in patients with chronic liver failure （CLF）in Guangxi, China, and to provide a scientific basis for TCM diagnosis and treatment and integrated traditional Chinese and Western medicine diagnosis and treatment of this disease. Methods ： A retrospective study was conducted in 1022 patients with CLF in Guangxi, and a statistical analysis was performed to investigate etiology ,TCM syndrome ,and prognosis. Results ：Liver cirrhosis was a high risk factor for CLF. Viral hepatitis,liver cirrhosis, and ethanol were the main causes of CLF, especially hepatitis B virus（HBV）. The identified syndrome elements of CLF mainly included blood stasis, qi deficiency, yang deficiency, damp -heat ,and heat toxin. The top three TCM syndromes were blood stasis -heat jaundice ,qi -deficiency and blood- stasis jaundice ,and yang - deficiency and blood - stasis jaundice. And the patients with syndrome of yang - deficien- cy and blood stasis jaundice or syndrome of spleen - kidney yang deficiency had a higher mortality. Conclusion ： The main causes of CLF are liver cirrhosis and HBV in Guangxi, China, and qi deficiency and yang deficiency are prom- inent among TCM syndromes. It has a great guiding significance for the clinical treatment of CLF.

关 键 词：慢性肝衰竭 中医证候 病因病机 回顾性分析 广西地区 

分 类 号：R259.753[医药卫生—中西医结合]