A late Neolithic expansion of Y chromosomal haplogroup O2a1-M95 from east to west  

作　　者：GaneshPrasad Arunkumar Lan-Hai Wei Valampuri John Kavitha Adhikarla Syama Varatharajan Santhakumari Arun Surendra Sathua Raghunath Sahoo R. Balakrishnan Tomo Riba Jharna Chakravarthy Bapukan Chaudhury Premanada Panda Pradipta K. Das Prasanna K. Nayak Hui Li Ramasamy Pitchappan 无 

机构地区：[1]The Genographic Laboratory, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, India [2]School of Chemical and Biotechnology, SASTRA University, Thanjavur 613401, India [3]MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200433, China [4]Department of Biotechnology, Mother Theresa University, Kodaikanal 624102, India [5]Project Coordinator, Sarba Sikhya Abjhijan, Rayagada, Orissa 765001, India [6]DND Agency-Bondo Project Leader (Retd), Rayagada Directorate, Bhubaneswar, Orissa 751004, India [7]Roja Muthiah Research Library, Taramani, Chennai 600113, India [8]Department of Geography, Rajiv Ghandhi University, Rnono Hills, Itanagar, Arunachal Pradesh 791112, India [9]Department of Zoology, Rajiv Ghandhi University, Rnono Hills, Itanagar, Arunachal Pradesh 791112, India [10]Department of Anthropology, Gauwhati University, Guwahati, Assam 781014, India [11]Department Anthropology, Sambalpur University, Jyoti Vihar, Sambalpur, Orissa 768019, India [12]Department of Anthropology, Guru Ghasidas Central University, Bilaspur, Chattisgarh 495009, India [13]Department of Anthropology, Utkal University, Vani Vihar, Bhubaneswar, Orissa 751004, India [14]Genomics Laboratory, Chettinad Academy of Research and Education, Kelampakkam, Chennai 603103, India [15]The Genographic Consortium

出　　处：《Journal of Systematics and Evolution》2015年第6期546-560,共15页植物分类学报（英文版）

摘　　要：The origin and dispersal of Y-Chromosomal haplogroup O2a1-M95, distributed across the Austro Asiatic speaking belt of East and South Asia, are yet to be fully understood. Various studies have suggested either an East indian or Southeast Asian origin of O2a1-M95. We addressed the issue of antiquity and dispersal of O2a1-M95 by sampling 8748 men from India, Laos, and China and compared them to 3307 samples from other intervening regions taken from the literature. Analyses of haplogroup frequency and Y-STR data on a total 2413 O2a1-M95 chromosomes revealed that the Laos samples possessed the highest frequencies of O2a1-M95 （74% with 〉0.5） and its ancestral haplogroups （O2^＊-P31, O^＊-M175） as well as a higher proportion of samples with 14STR-median haplotype （17 samples in 14 populations）, deep coalescence time （5.7 ± 0.3 Kya） and consorted O2a1-M95 expansion evidenced from STR evolution. All these suggested Laos to carry a deep antiquity of O2a1-M95 among the study regions. A serial decrease in expansion time from east to west： 5.7 ±0.3 Kya in Laos, 5.2± 0.6 in Northeast India, and 4.3 ± 0.2 in East india, suggested a late Neolithic east to west spread of the lineage O2a1-M95 from Laos.The origin and dispersal of Y-Chromosomal haplogroup O2a1-M95, distributed across the Austro Asiatic speaking belt of East and South Asia, are yet to be fully understood. Various studies have suggested either an East indian or Southeast Asian origin of O2a1-M95. We addressed the issue of antiquity and dispersal of O2a1-M95 by sampling 8748 men from India, Laos, and China and compared them to 3307 samples from other intervening regions taken from the literature. Analyses of haplogroup frequency and Y-STR data on a total 2413 O2a1-M95 chromosomes revealed that the Laos samples possessed the highest frequencies of O2a1-M95 （74% with 〉0.5） and its ancestral haplogroups （O2^＊-P31, O^＊-M175） as well as a higher proportion of samples with 14STR-median haplotype （17 samples in 14 populations）, deep coalescence time （5.7 ± 0.3 Kya） and consorted O2a1-M95 expansion evidenced from STR evolution. All these suggested Laos to carry a deep antiquity of O2a1-M95 among the study regions. A serial decrease in expansion time from east to west： 5.7 ±0.3 Kya in Laos, 5.2± 0.6 in Northeast India, and 4.3 ± 0.2 in East india, suggested a late Neolithic east to west spread of the lineage O2a1-M95 from Laos.

关 键 词：Laos migration NEOLITHIC NRY O2a1-M95. 

分 类 号：Q987.1[生物学—遗传学] K878[生物学—人类学]