维吾尔族、汉族围绝经期抑郁症患者女性激素水平和社会心理因素的对比  

Comparison of hormones levels and psychosocial factors between Han and Uygur perimenopausal depression women

作　　者：李月娥[1] 徐上知[2] 吕淑云[1] 马瑞晨[1] 杨超[1] 王欣[1] 巴哈尔古丽[1] 

机构地区：[1]新疆维吾尔自治区乌鲁木齐市第四人民医院临床心理科,新疆乌鲁木齐830002 [2]石河子大学医学院预防医学系

出　　处：《中国妇幼保健》2015年第35期6333-6336,共4页Maternal and Child Health Care of China

基　　金：新疆维吾尔自治区卫生厅青年科技人才专项资助项目〔2013Y25〕

摘　　要：目的探讨维吾尔族、汉族围绝经期抑郁症患者女性激素水平和社会心理因素的差异。方法选取2013年5月-2014年12月在该院心理科住院的围绝经期抑郁症患者122例为研究对象,其中汉族70例、维吾尔族52例。两组患者均进行一般情况调查表、紧张性生活事件评定量表(SLERS)、艾森克人格特征问卷(EPQ)、OLSON婚姻质量问卷(ENRICH)、汉密尔顿抑郁量表(HAMD)的评估。并于清晨空腹状态下采取外周静脉血进行雌二醇(E2)、孕酮(P)水平的测定。结果两组患者文化程度、绝望感、焦虑躯体化、恶性生活事件、健康、婚姻满意度、性格相容性、业余活动、性生活、角色平等性比较,差异有统计学意义(P<0.05)。两组雌激素、孕激素水平比较,差异无统计学意义(P>0.05)。汉族患者的多元逐步回归分析发现,婚姻满意度与HAMD评分呈负相关,神经质、法律政治负性事件与HAMD评分呈正相关。维吾尔族患者的多元逐步回归分析发现,内外向、遇到烦恼获得支持、与亲友关系、婚姻满意度、文化程度与HAMD评分呈负相关,健康与HAMD评分呈正相关。两组多元逐步回归分析均显示,雌激素、孕激素水平与HAMD评分相关性较小。结论汉族和维吾尔维围绝经期抑郁症的发生是多种社会心理因素综合作用的结果。汉族和维吾尔维围绝经期抑郁症患者的社会心理因素存在一定的差异。雌激素、孕激素水平与围绝经期抑郁症的相关性较小。Objective To explore the differences of hormones levels and psychosocial factors between Han and Uygur perimenopa- usal depression women. Methods A total of 122 perimenopausal depression patients were selected from Department of Psychology in the hospital from May 2013 to December 2014 as study objects, including 70 Han women and 52 Uygur women; the women in the two groups were surveyed by general information questionnaire, SLERS, EPQ, ENRICH, and HAMD; morning fasting peripheral blood specimens were obtained to detect estradiol and progesterone levels. Results There were statistically significant differences in educational level, sense of de- spair, anxiety/somatization, malignant life events, health, marital satisfaction, character compatibility, extracurricular activities, sex life, and role equality between the two groups （ P〈0. 05 ） ; there was no statistically significant difference in the levels of estradiol and progesterone between the two groups （ P〉0.05 ） ; multivariate stepwise regression analysis for Han women showed that marital satisfaction was negatively correlated with HAMD score, neuroticism, legal and political events were positively correlated with HAMD score; multivariate stepwise re- gression analysis for Uygur women showed that introversion or extroversion, obtaining support when encountering annoyance, relationship with relatives and friends, marital satisfaction, and educational level were negatively correlated with HAMD score, health was. positively correlated with HAMD score; multivariate stepwise regression analysis in the two groups both showed that the levels of estradiol and progesterone were slightly correlated with HAMD score. Conclusion The occurrence of perimenopausal depression among Uygur and Han women is a result of comprehensive effects of various social and psychological factors; there is a certain difference in psychosocial factors among Uygur and Han perimenopausal depression women; the levels of estradiol and progesterone are slightly correlated with perimenop

关 键 词：围绝经期 抑郁症 婚姻质量 生活事件 雌激素类 维吾尔族 

分 类 号：R173[医药卫生—妇幼卫生保健]