贯穿缝合式胰肠吻合的研究  

Animal experimental study on penetrating -suture pancreaticojejunostomy

作　　者：朱学锋[1] 陈益君[1] 朱永胜[1] 黄建军[1] 曹亮亮[2] 周萍[3] 王雪磊[1] 余健[2] 朱正龙[3] 

机构地区：[1]江苏省泰兴市人民医院肝胆外科,225400 [2]江苏省泰兴市人民医院麻醉科,225400 [3]江苏省泰兴市人民医院病理科,225400

出　　处：《中华实验外科杂志》2015年第12期3058-3061,共4页Chinese Journal of Experimental Surgery

基　　金：江苏省卫生厅医学科研招标课题（YG201303）

摘　　要：目的探讨贯穿缝合式胰肠吻合的病理过程和验证该吻合方法临床应用的可行性和安全性。方法术中测定胰肠吻合口的耐受压；术后不同时间段处死家猪剖腹探查和病理检查了解胰腺空肠之间愈合和病理演变过程。结果本组家猪均顺利完成贯穿缝合式胰肠吻合。胰肠吻合时间为4～8min，平均6min。术中测定吻合口耐受压均达60cmH2O（1cmH2O=0．098kPa）。术后不同时间段处死家猪见胰肠吻合口对合良好、连接紧密，无腹腔积液，无吻合口出血、瘘。连续的病理检查显示出胰肠吻合口炎性反应、肉芽组织增生和瘢痕形成的良好愈合过程。结论贯穿缝合式胰肠吻合操作简便、吻合可靠、愈合较快，胰腺断面胰液引流畅。Objective To explore the pathological process and evaluate the feasibility and safety of penetrating - suture pancreatieojejunostomy by animal experiment. Methods The tolerance pressure of the anastomotic intestine was measured during surgery. Exploratory laparotomy and pathological examination on executed pig was performed at different time after panceaticojejunostomy. Results The anastomosis with penetrating - suture pancreaticojejunostomy was performed successfully in all pigs. The time of anastomosis was from four minutes to eight minutes, average of 6 minutes. The tolerance pressure of the anastomotic in- testine in all pigs was 60 emil20 （1 emil20 = 0. 098 kPa）at least. Bleeding, fistula or seroperitoneum was not found in exploratory laparotomy and the interface of pancreaticoenterostomy was satisfactory with com- pact connection. Successional pathological examination showed the favourable anastomotic process including inflammation, granulation hyperplasia and scar healing. Conclusion Penetrating - suture pancreaticojeju- nostomy is simple, reliable and the heal is quicker. The drainage of exudation from pancreatic section is unhindered. It is worthy of clinical popularization and application.

关 键 词：贯穿缝合式胰肠吻合 胰瘘 家猪 

分 类 号：R657.5[医药卫生—外科学]