新鲜血浆与去冷沉淀血浆中血型抗体效价及血浆蛋白的含量的比较  

Comparison of the titers of blood group antibody and the content of plasma proteins between the fresh plasma and the cryoprecipitate-reduced plasma

作　　者：李福照 

机构地区：[1]河南省新县人民医院输血科,465550

出　　处：《中国实用医刊》2015年第24期24-25,共2页Chinese Journal of Practical Medicine

摘　　要：目的 比较新鲜血浆与去冷沉淀血浆中血型抗体效价及血浆蛋白的含量.方法 选取70例新鲜血浆和60例去冷沉淀血浆开展研究,均行血型抗体、血浆蛋白和凝血因子检测.结果 新鲜血浆A型抗-B、B型抗-A、0型抗-A、0型抗-B抗体效价分别为4.61±1.05、3.82±1.19、4.80±1.02、4.58±1.10,均低于去冷沉淀血浆,差异有统计学意义（P＜0.05）.新鲜血浆Ⅴ因子、Ⅷ因子、X因子分别为73.26±3.96、69.22±4.87、69.24±5.62,高于去冷沉淀血浆,差异有统计学意义（P＜0.05）.新鲜血浆A型、B型、O型总蛋白、球蛋白、白蛋白均低于去冷沉淀血浆,差异有统计学意义（P＜0.05）.结论 去冷沉淀血浆制备过程中可能影响血型抗体效价、凝血机制等,在临床应用中具有局限性.Objective To compare the titers of blood group antibody and the content of plasma proteins between the fresh plasma and the cryoprecipitate-reduced plasma.Methods Seventy cases of the fresh plasma and 60 cases of the cryoprecipitate-reduced plasma were selected as the research objects, and then the blood group antibodies, plasma proteins and clotting factors were detected.Results The antibody titers of A type anti-B, B-type anti-A, 0 anti-A, 0 anti-B in the fresh plasma respectively were 4.61 ± 1.05,3.82 ± 1.19,4.80 ± 1.02,4.58 ± 1.10, which were lower than the those of the cryoprecipitate-reduced plasma, and the differences were significant （P 〈 0.05）.Factor Ⅴ, Ⅷ factor, X factor in the fresh plasma respectively were 73.26 ± 3.96, 69.22 ± 4.87, 69.24 ± 5.62, which were all higher than those of the cryoprecipitate-reduced plasma, the differences were significant （P 〈 0.05）.The levels of Atype albumin, B-type albumin, O-total albumin, globulin, albumin in the fresh plasma were all lower than those of the cryoprecipitate-reduced plasma, and the differences were significant （P 〈 0.05）.Conclusions In the preparation process of the cryoprecipitate-reduced plasma, blood antibody titer, blood clotting mechanisms and other things are affected, and there are limitations in the clinical application.

关 键 词：新鲜血浆 去冷沉淀血浆 血型抗体 血浆蛋白 

分 类 号：R714.43[医药卫生—妇产科学]