青岛市大龄女性性工作者梅毒感染影响因素分析  

Influencing factors of syphilis infection among older female sex workers in Qingdao city

作　　者：许意清 李宜霏 姜珍霞 张西江[2] 袁雪[2] 张宁 李秀芳[4] 姜宝法[1] 

机构地区：[1]山东大学公共卫生学院流行病学系,山东济南250012 [2]青岛市疾病预防控制中心 [3]胶州市爱心健康咨询检测中心 [4]青岛大学医学院附属医院

出　　处：《中国公共卫生》2015年第12期1525-1529,共5页Chinese Journal of Public Health

基　　金：美国国立卫生研究所基金(5R01HD068305-02)

摘　　要：目的了解山东省青岛市大龄女性性工作者（OFSWs）艾滋病（AIDS）和梅毒感染状况及影响因素，为制定预防干预措施提供依据。方法2014年3—6月采用同伴驱动抽样方法（RDS）招募到420名青岛市OFSWs进行问卷调查和AIDS及梅毒血清学检测。结果样本人群平均年龄为（42．6±6．3）岁，以汉族、离异／丧偶者、外地户籍和初中及以下文化程度为主，经检验样本具有代表性；血清学检测未发现艾滋病病毒（HIV）感染者；发现125例梅毒既往感染者，其中36例为现患梅毒感染者，经校正后感染率分别为31．8％和9．1％；多因素logistic逐步回归分析结果表明，青岛本地户籍（OR=2．082，95％C／=1．310～3．310）、吸毒（OR=2．006，95％CI=1．161—3．466）、初次性交易年龄〉35岁（OR=1．779，95％C／=1．133～2．791）、性工作时间〉14年（OR=1．930，95％C／=1．100—3．384）是青岛市OFSWs既往梅毒感染的危险因素。结论青岛市OFSWs梅毒既往感染率高，感染和传播AIDS的风险也日渐增加。Objective To investigate the prevalence and risk factors of human immunodeficiency virus （HIV） and syphilis infection among older female sex workers （OFSWs）in Qingdao city, China and to provide evidences for making prevention and intervention strategies. Methods Totally 420 women aged ≥35 years,residing in Qingdao city at least 3 months, and having one or more commercial sex behavior during the previous one month were recruited with respondentdriven sampling（ RDS ） method between March and May 2014. The participants were surveyed with a questionnaire face- to-face and serum test for HIV and syphilis infection. Results A statistics verified representative sample of OFSWs was recruited and the average age of the participants was 42.6 ± 6.4 years ; most of the participants were Han ethnic, divorced or widowed, without local census register, and with the primary school or lower education. No HIV positive cases was identified among the participants. Among participants, 125 had prior and 36 had current syphilis infection; the RDS-adjusted lifetime prevalence of syphilis was 31.8 % and the active prevalence of syphilis was 9. 1%. The result of multivariate logistic stepwise regression showed that with local census register（ odds ratio [ OR ] =2. 082,95% confidence interval [ 95 % CI ] = 1.310 - 3.310 ）, drug-use behavior （ OR = 2. 006,95 % CI = 1.161 - 3.466 ）, having commercial sex after the age of 35 years （ OR = 1. 779,95% CI = 1. 133 - 2.791 ）, and with a duration of commercial sex over 4 years （ OR = 1. 930,95 % CI = 1. 100 - 3. 384 ） were factors related to the lifetime syphilis infection among the participants. Conclusion The serum prevalence of syphilis infection is high, suggesting an increased risk of HIV transmission among OFSWs in Qingdao city.

关 键 词：大龄女性性工作者(OFSWs) 同伴驱动抽样(RDS) 艾滋病(AIDS) 梅毒 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]