尿路感染病原菌分布与耐药性分析  

Species distribution and antimicrobial resistance of pathogens causing urinary tract infections

作　　者：刘传江[1] 杨家宏 周凤英[1] 张燕英[1] 周光宏[1] 

机构地区：[1]麻城市人民医院检验科,湖北麻城438300 [2]广水市第一人民医院检验科,湖北广水432700

出　　处：《中华医院感染学杂志》2015年第24期5567-5569,共3页Chinese Journal of Nosocomiology

基　　金：湖北省卫生厅基金资助项目(30214078)

摘　　要：目的探讨医院尿路感染病原菌的分布及耐药现状,指导医师合理选择抗菌药物,提高尿路感染的临床治愈率。方法采集2012年1-12月尿路感染患者尿液标本,对其进行病原菌分离培养、菌落计数、菌种鉴定,药敏试验采用CLSI规定的K-B法,数据采用SPSS 17.0软件进行统计分析。结果共调查患者2 059例,其中确诊为尿路感染333例,尿路感染率为16.2%;送检尿液标本703份,检出病原菌阳性237例,阳性检出率33.7%;共分离出病原菌237株,以大肠埃希菌主,共128株占54.0%。结论临床医师应注重尿路感染的病原学培养和耐药性检测,规范临床用药行为,提高感染性疾病的治疗水平。OBJECTIVE To discuss the distribution and antimicrobial resistance of pathogenic bacteria causing urinary tract infections to guide the clinician to use the antibiotics reasonably and raise the recovery rate. METHODS Urine samples were collected from 2059 patients by the aseptic technique from Jan. 2012 to Dec. 2012 to perform bacterial isolating, culture, colony counts and identification referring to National Guide to Clinical Laboratory Procedures. Susceptibility testing was carried out by K-B method recommended by CLSI. Data were statistically analyzed by software SPSS 17.0. RESULTS Among the 2 059 patients, 333 were confirmed to have urinary tract infections. Among the 703 urine samples, 237 pathogenic bacteria were isolated as positive： The positive rate was 33.7%. The main bacteria were Escherichia coli （128 strains, 54.0%）. CONCLUSION The clinician should attach importance to etiology and resistance testing of urinary tract infections to regulate the behavior of clinical medicine and improve the treatment of infectious diseases.

关 键 词：尿路感染 病原菌 构成比 耐药性 药敏试验 

分 类 号：R378[医药卫生—病原生物学]