MR对大脑中动脉流速编码的设置及其影响因素的研究  

Study on the setting of the middle cerebral artery flow velocity in encoding and its influencing factors

作　　者：刘军波[1] 范丽娟[1] 张晓浩[1] 管延芳[1] 于铁链[2] 

机构地区：[1]天津医科大学心血管临床学院泰达国际心血管病医院放射科,天津300457 [2]天津医科大学总医院放射科,天津300052

出　　处：《医学影像学杂志》2015年第12期2106-2109,共4页Journal of Medical Imaging

基　　金：天津市滨海新区卫生局重点支持科技项目(2013BWKZ008)

摘　　要：目的 采用1.5T磁共振相位对比法（PC-MR）测量大脑中动脉（MCA）血流,探讨不同编码速率（Venc）对MCA血流信号的影响及其与性别、年龄和血压的关系。方法 对63例健康受检者,男36例,女27例,年龄20~75岁,平均（48.1±9.6）岁,分别按性别、年龄、收缩压及舒张压分组。每例预置Venc：55cm/s、65cm/s、75cm/s、85cm/s、95cm/s,对左侧MCA进行5次扫描。在工作站上测得不同Venc相对应的左侧MCA的信号强度,并进行统计学分析。结果不同预置Venc左侧MCA信号强度差别有统计学意义（F=11.852,P=0.000）,Venc 85cm/s时信号最强。Venc预置85cm/s时,左侧MCA信号强度在不同性别（t=-1.301,P=0.198）、年龄组（F=2.098,P=0.132）及不同收缩压组（F=1.051,P=0.356）之间差别无统计学意义;在不同舒张压组间差别有统计学意义（F=3.598,P=0.033）,舒张压〉80mmHg时,左侧MCA信号强度减低。结论 MCA PC-MR测量的最佳Venc为85cm/s。MCA血流信号与性别、年龄和收缩压无关;与舒张压有关,信号强度随着舒张压升高而减低。Objective To explore the influences of 1.5 T MR cine phase contrast （PC-MR） technique with different venc on the blood flow measurements in the middle cerebral artery （MCA）, and to assess the blood flow according to sex, age and blood pressure. Methods 63 healthy volunteers （36 males and 27 females; age range 20-75 years; mean age 48.1± 9.6 years） were selected in the study. The volunteers were divided into different groups by sex, age, systolic blood pres sure and diastolic blood pressure, respectively. For every volunteer, the left MCA was scanned for 5 times repeatedly, with the venc of 55, 65, 75, 85 and 95 cm/s separately. The signal intensity of the left MCA of different venc was meas- ured on the workstation, and the statistical analysis was carried out. Results The signal intensity of the left MCA with different venc showed statistical significance （ F = 11. 852, P =0. 000）. When venc was set at 85cm/s, the signal intensi- ty was the strongest. The left MCA signal intensity was independent of sex （ t =1. 301, P =0. 198）, age group （ F = 2. 098, P =0. 132）, and systolic blood pressure group （ F =1. 051, P =0. 356）, when venc was set at 85 cm/s. There was a significant difference （ F = 3. 598, P =0. 033） among diastolic blood pressure group, and when diastolic blood pres sure was higher than 80 mmHg, the left MCA signal intensity was reduced significantly. Conclusion The best venc for PC MR MCA measurement was 85 cm/s. MCA blood flow signal intensity was independent of sex, age and systolic blood pressure, but which was decreased with the increase of diastolic blood pressure.

关 键 词：磁共振成像 相位对比 大脑中动脉 编码速率 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743[医药卫生—诊断学]